Detailed information of TA system TA093834

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 1326444..1326951
• Replicon: chromosome
• Accession: NZ_CP026332
• Organism: Pseudomonas sp. XWY-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PRJ_RS06280
• Protein ID: WP_104960954.1
• Coordinates: 1326673..1326951 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PRJ_RS06275
• Protein ID: WP_064492302.1
• Coordinates: 1326444..1326683 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PRJ_RS06260	1321993..1322874	-	882	WP_104960951.1	SMP-30/gluconolactonase/LRE family protein	-
PRJ_RS06265	1322897..1323703	-	807	WP_104960952.1	NAD(P)-dependent oxidoreductase	-
PRJ_RS06270	1324387..1325625	-	1239	WP_104960953.1	OprD family porin	-
PRJ_RS06275	1326444..1326683	+	240	WP_064492302.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PRJ_RS06280	1326673..1326951	+	279	WP_104960954.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PRJ_RS06285	1327262..1327768	-	507	Protein_1160	Bro-N domain-containing protein	-
PRJ_RS06290	1328018..1328752	-	735	WP_104960955.1	zeta toxin family protein	-
PRJ_RS06295	1328739..1329002	-	264	WP_021784483.1	hypothetical protein	-
PRJ_RS06300	1329343..1329879	-	537	WP_104960956.1	Bro-N domain-containing protein	-
PRJ_RS29785	1330301..1331017	-	717	WP_147429954.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-76)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-70)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10817.61 Da
• Isoelectric Point: 10.2806

>T93834 WP_104960954.1 NZ_CP026332:1326673-1326951 [Pseudomonas sp. XWY-1]
MTYSLDFDARALKEWKKLGDTVRQQFKKKLAEVLLKSRIEANRLHSLPDCYKIKLRSSGYRLVYQVIDQEIVVLVVAVDR
RERDQAHKKAAE

Nucleotide

• Length: 279 bp

>T93834 NZ_CP026332:1326673-1326951 [Pseudomonas sp. XWY-1]
ATGACCTATAGCCTCGACTTCGATGCCCGCGCATTGAAGGAGTGGAAGAAGCTGGGCGATACCGTGCGTCAGCAGTTCAA
GAAGAAACTGGCAGAGGTCCTGCTGAAATCTCGAATCGAGGCAAACCGCCTTCACTCGCTGCCAGATTGCTACAAAATAA
AGCTTCGCAGCAGTGGGTACAGGCTGGTCTATCAGGTCATTGACCAAGAGATCGTGGTTCTTGTCGTCGCTGTCGATCGT
CGTGAGCGGGACCAAGCTCACAAAAAGGCTGCTGAGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9097.44 Da
• Isoelectric Point: 4.6310

>AT93834 WP_064492302.1 NZ_CP026332:1326444-1326683 [Pseudomonas sp. XWY-1]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLGSPQRVRVQLDDL

Nucleotide

• Length: 240 bp

>AT93834 NZ_CP026332:1326444-1326683 [Pseudomonas sp. XWY-1]
ATGGCTTCCATCAACATCCGCGTCGACGATGATCTCAAAGCCCGCGCCTACAAAGAGCTCGAGCGCCTCGGTGTAACCCC
CTCCGAGCTCATGCGGCAGGCTCTGCAATATGTCGCTGAGCGGGGCAAGCTACCCTTCAGGCCAGTCCTTATGACCGAGG
AAGATGAAGACCTCATTGCGACCGTACAAGAGCGTCTTGGTTCTCCGCAGCGCGTGAGGGTCCAGCTGGATGACCTATAG