Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 1411127..1411692 | Replicon | chromosome |
| Accession | NZ_CP026321 | ||
| Organism | Vibrio campbellii strain BoB-53 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | C1N50_RS07025 | Protein ID | WP_046875151.1 |
| Coordinates | 1411405..1411692 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3BLE1 |
| Locus tag | C1N50_RS07020 | Protein ID | WP_000086647.1 |
| Coordinates | 1411127..1411408 (+) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1N50_RS06980 | 1407081..1407173 | + | 93 | WP_102561750.1 | DUF3265 domain-containing protein | - |
| C1N50_RS06985 | 1407214..1407621 | + | 408 | WP_103412986.1 | hypothetical protein | - |
| C1N50_RS06990 | 1407942..1408811 | + | 870 | WP_103413776.1 | hypothetical protein | - |
| C1N50_RS06995 | 1408917..1409522 | + | 606 | WP_103412987.1 | hypothetical protein | - |
| C1N50_RS07000 | 1409658..1410164 | + | 507 | WP_103412988.1 | hypothetical protein | - |
| C1N50_RS07005 | 1410179..1410271 | + | 93 | WP_072605894.1 | DUF3265 domain-containing protein | - |
| C1N50_RS07010 | 1410358..1410918 | + | 561 | WP_103412989.1 | hypothetical protein | - |
| C1N50_RS07015 | 1410944..1411036 | + | 93 | WP_080765254.1 | DUF3265 domain-containing protein | - |
| C1N50_RS07020 | 1411127..1411408 | + | 282 | WP_000086647.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| C1N50_RS07025 | 1411405..1411692 | + | 288 | WP_046875151.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| C1N50_RS25760 | 1411720..1411812 | + | 93 | WP_005445734.1 | DUF3265 domain-containing protein | - |
| C1N50_RS07030 | 1411848..1412507 | + | 660 | WP_103412991.1 | HAD family hydrolase | - |
| C1N50_RS07035 | 1412480..1412614 | + | 135 | WP_140078509.1 | DUF3265 domain-containing protein | - |
| C1N50_RS07040 | 1412755..1413234 | + | 480 | WP_103412992.1 | type VI secretion system amidase effector protein Tae4 | - |
| C1N50_RS07045 | 1413249..1413581 | + | 333 | WP_103413778.1 | hypothetical protein | - |
| C1N50_RS07050 | 1413596..1413688 | + | 93 | WP_196333444.1 | DUF3265 domain-containing protein | - |
| C1N50_RS07055 | 1413717..1414121 | + | 405 | WP_103412993.1 | DUF1801 domain-containing protein | - |
| C1N50_RS07060 | 1414281..1414736 | + | 456 | WP_103412994.1 | GNAT family N-acetyltransferase | - |
| C1N50_RS07065 | 1414853..1415380 | + | 528 | WP_103412995.1 | hypothetical protein | - |
| C1N50_RS25765 | 1415403..1415492 | + | 90 | Protein_1263 | DUF3265 domain-containing protein | - |
| C1N50_RS07075 | 1415526..1416287 | + | 762 | WP_103412996.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1365505..1444722 | 79217 | |
| - | flank | IS/Tn | - | - | 1416313..1417089 | 776 | |
| - | inside | Integron | - | - | 1363760..1427815 | 64055 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10997.68 Da Isoelectric Point: 5.1098
>T93816 WP_046875151.1 NZ_CP026321:1411405-1411692 [Vibrio campbellii]
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNEVFDKTELLGSMPEMGRLVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNEVFDKTELLGSMPEMGRLVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV
Download Length: 288 bp
>T93816 NZ_CP026321:1411405-1411692 [Vibrio campbellii]
ATGAAAGTAGTCTGGTCTCCATTAGCACTTCAGAAACTAGGTGATGCAGCGGAGTTTATTTCTTTGGATAATCCACCTGC
AGCAGAGAGGTGGGTAAACGAAGTTTTTGATAAAACTGAACTACTTGGAAGTATGCCTGAAATGGGGCGGCTTGTTCCTG
AAATGCCCCACACGAACTATCGCGAAATCATCTTTGGTCACTATCGTATTATCTACAGTTTAAGTCACGAAATCCGCGTA
CTAACAGTTCGTAATTGTCGTCAAATTTTATCGGAAGATGACGTGTAA
ATGAAAGTAGTCTGGTCTCCATTAGCACTTCAGAAACTAGGTGATGCAGCGGAGTTTATTTCTTTGGATAATCCACCTGC
AGCAGAGAGGTGGGTAAACGAAGTTTTTGATAAAACTGAACTACTTGGAAGTATGCCTGAAATGGGGCGGCTTGTTCCTG
AAATGCCCCACACGAACTATCGCGAAATCATCTTTGGTCACTATCGTATTATCTACAGTTTAAGTCACGAAATCCGCGTA
CTAACAGTTCGTAATTGTCGTCAAATTTTATCGGAAGATGACGTGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10398.91 Da Isoelectric Point: 5.8650
>AT93816 WP_000086647.1 NZ_CP026321:1411127-1411408 [Vibrio campbellii]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
Download Length: 282 bp
>AT93816 NZ_CP026321:1411127-1411408 [Vibrio campbellii]
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCTTTGTCTGAGTTTCGTGCCGGTGTAGCTTCATACATCAAACAAAT
CAATGAGACTCGTCGCCCATTGGTTATTACGCAACGTGGCAAAGGTGTTGCTGTTGTTCTCGATGTTGCTGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTGGAAGAAATGCGCACTGCAGAAGCTCAGTTAGCTTCTGGTCTCGGTGTTTCCAAT
GATGATGCGCGTGCTCAAGTACTTGGGCGCATTAAAAAATGA
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCTTTGTCTGAGTTTCGTGCCGGTGTAGCTTCATACATCAAACAAAT
CAATGAGACTCGTCGCCCATTGGTTATTACGCAACGTGGCAAAGGTGTTGCTGTTGTTCTCGATGTTGCTGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTGGAAGAAATGCGCACTGCAGAAGCTCAGTTAGCTTCTGGTCTCGGTGTTTCCAAT
GATGATGCGCGTGCTCAAGTACTTGGGCGCATTAAAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|