Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2027231..2027750 Replicon chromosome
Accession NZ_CP026265
Organism Aminobacter sp. MSH1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CO731_RS10130 Protein ID WP_108606985.1
Coordinates 2027469..2027750 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CO731_RS10125 Protein ID WP_108606984.1
Coordinates 2027231..2027479 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO731_RS10110 2022375..2023334 - 960 WP_108606981.1 ABC transporter permease -
CO731_RS10115 2023351..2024934 - 1584 WP_108606982.1 ABC transporter substrate-binding protein -
CO731_RS10120 2025077..2027083 - 2007 WP_108606983.1 CocE/NonD family hydrolase -
CO731_RS10125 2027231..2027479 + 249 WP_108606984.1 plasmid stabilization protein Antitoxin
CO731_RS10130 2027469..2027750 + 282 WP_108606985.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CO731_RS10135 2027758..2028351 - 594 WP_108606986.1 nucleoside deaminase -
CO731_RS10140 2028356..2028856 - 501 WP_108609738.1 ureidoglycolate lyase -
CO731_RS10145 2028878..2029723 - 846 WP_108606987.1 (S)-ureidoglycine aminohydrolase -
CO731_RS10150 2029729..2031162 - 1434 WP_108606988.1 allantoinase PuuE -
CO731_RS10155 2031341..2031706 + 366 WP_108606989.1 hydroxyisourate hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11044.89 Da        Isoelectric Point: 10.6209

>T93753 WP_108606985.1 NZ_CP026265:2027469-2027750 [Aminobacter sp. MSH1]
MRYEVEFLETALKEWKALDANTREHFRKKLKERCENPRVPSAKLHGAKDRYKIKLRSAGYRLVYEVEDGRLVVLVIAIGR
RDRLEVYAKAARR

Download         Length: 282 bp

>T93753 NZ_CP026265:2027469-2027750 [Aminobacter sp. MSH1]
ATGCGCTATGAGGTCGAGTTCCTCGAAACCGCACTGAAGGAATGGAAAGCGCTCGACGCCAATACACGCGAGCACTTCCG
CAAGAAGCTGAAGGAGCGCTGTGAAAACCCGCGCGTCCCCTCGGCCAAGCTGCATGGCGCCAAGGACCGCTACAAGATCA
AGCTGCGAAGTGCCGGCTATCGCCTTGTCTACGAGGTGGAGGATGGCAGGCTGGTGGTGCTGGTCATCGCCATAGGCCGG
CGCGACCGCCTCGAGGTTTATGCCAAGGCGGCGAGGCGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8933.31 Da        Isoelectric Point: 4.5702

>AT93753 WP_108606984.1 NZ_CP026265:2027231-2027479 [Aminobacter sp. MSH1]
MPNTVLAEVTASVSELKRNPMGTVAAGEGFPVAILNRNEPAFYCVPAKAFEAMMDRLEDIELNAIADARKGEKRIRVDLD
AL

Download         Length: 249 bp

>AT93753 NZ_CP026265:2027231-2027479 [Aminobacter sp. MSH1]
ATGCCGAACACAGTTCTTGCCGAAGTTACTGCCAGCGTCTCGGAGCTGAAAAGGAACCCGATGGGCACGGTGGCTGCCGG
GGAAGGGTTTCCGGTCGCCATTCTCAATCGCAACGAACCGGCCTTCTACTGCGTGCCTGCCAAGGCCTTCGAGGCGATGA
TGGACCGGCTGGAGGACATCGAGCTCAACGCGATTGCCGACGCGCGCAAGGGCGAAAAGCGTATCCGGGTCGACCTGGAT
GCGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References