Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 2504660..2505624 Replicon chromosome
Accession NZ_CP026228
Organism Aeromonas sp. ASNIH1

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag C2U37_RS12210 Protein ID WP_104452382.1
Coordinates 2504660..2505067 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag C2U37_RS12215 Protein ID WP_104452383.1
Coordinates 2505067..2505624 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U37_RS12195 2500945..2502006 + 1062 WP_104452379.1 phage portal protein -
C2U37_RS12200 2502468..2503475 - 1008 WP_104452380.1 DUF4062 domain-containing protein -
C2U37_RS12205 2503558..2504181 - 624 WP_104452381.1 hypothetical protein -
C2U37_RS24625 2504213..2504470 - 258 WP_158656247.1 ash family protein -
C2U37_RS12210 2504660..2505067 - 408 WP_104452382.1 hypothetical protein Toxin
C2U37_RS12215 2505067..2505624 - 558 WP_104452383.1 SocA family protein Antitoxin
C2U37_RS24630 2505722..2505868 - 147 WP_158656248.1 hypothetical protein -
C2U37_RS12220 2506075..2506245 + 171 Protein_2315 DUF4113 domain-containing protein -
C2U37_RS12225 2506251..2506592 - 342 WP_104452384.1 hypothetical protein -
C2U37_RS12230 2506594..2506806 - 213 WP_005308768.1 hypothetical protein -
C2U37_RS12235 2506821..2509199 - 2379 WP_104452385.1 replication endonuclease -
C2U37_RS12240 2509196..2509534 - 339 WP_104453234.1 hypothetical protein -
C2U37_RS12245 2509774..2509980 - 207 WP_104452386.1 hypothetical protein -
C2U37_RS12250 2509977..2510294 - 318 WP_104452387.1 hypothetical protein -
C2U37_RS12255 2510291..2510473 - 183 WP_104452388.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2475565..2516866 41301


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(27-139)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14990.29 Da        Isoelectric Point: 7.4145

>T93723 WP_104452382.1 NZ_CP026228:c2505067-2504660 [Aeromonas sp. ASNIH1]
MSIALVRRGTLLIPSGATNHLFFVCNDPILYPRNTKASFLAVNISSIAPNIEHDRTCVLDVGDHPFVHHPSFVFYRKAEI
FGAATVGEQIAAGDIQTHAICEEPTFARILAGFDLSPHVTPLIRNFYRKYCLPQP

Download         Length: 408 bp

>T93723 NZ_CP026228:c2505067-2504660 [Aeromonas sp. ASNIH1]
ATGTCGATAGCACTCGTGCGAAGAGGCACGCTGCTGATCCCATCGGGCGCAACCAATCATCTGTTTTTTGTCTGTAACGA
CCCCATTCTTTACCCCAGAAACACCAAAGCAAGCTTTCTTGCGGTCAATATCAGCAGCATCGCCCCCAACATCGAGCATG
ATCGGACTTGTGTGCTTGATGTGGGGGATCACCCTTTCGTGCACCACCCTAGTTTTGTCTTTTACCGCAAAGCCGAGATT
TTCGGTGCAGCAACGGTCGGCGAACAAATCGCGGCTGGTGACATTCAAACCCACGCCATCTGTGAAGAGCCAACCTTTGC
ACGCATCTTGGCCGGGTTTGACCTGTCTCCACACGTCACCCCCTTGATCCGCAACTTCTATCGTAAATACTGCCTTCCCC
AACCCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21301.06 Da        Isoelectric Point: 5.3199

>AT93723 WP_104452383.1 NZ_CP026228:c2505624-2505067 [Aeromonas sp. ASNIH1]
MFNEERVAQMAAFLLSKRGGRMAYLKLMKLLYLSDRESMSRFGESISGDLMVSMPHGPVLSQTLNLIRGGGEHADGWNEW
ISGEANYEVAIRRNVSDRDDFDLLSDVDLEILTKVWHEFGHMTRYQIRDYTHDHCPEWQDPRGSAYPIKEEDLFLAVGKS
PEVAGAMAQHLREQRQLDEITSRLR

Download         Length: 558 bp

>AT93723 NZ_CP026228:c2505624-2505067 [Aeromonas sp. ASNIH1]
ATGTTTAACGAAGAGCGTGTGGCACAAATGGCCGCCTTCCTGCTTTCCAAGCGGGGCGGACGAATGGCATACCTCAAACT
GATGAAACTGCTCTACCTGAGTGATCGGGAGTCCATGAGCCGTTTCGGTGAATCCATCAGCGGAGACCTCATGGTGTCCA
TGCCCCATGGGCCCGTGCTGTCACAGACGTTGAATCTGATCCGCGGTGGCGGTGAGCATGCTGACGGCTGGAATGAGTGG
ATCTCGGGCGAAGCGAATTACGAGGTGGCAATCCGTCGCAACGTGTCCGACCGGGACGACTTCGACTTGCTCAGCGATGT
GGATTTGGAAATCCTGACCAAGGTATGGCACGAGTTTGGGCACATGACTCGATACCAAATCCGTGACTACACCCATGACC
ATTGCCCGGAGTGGCAAGACCCCAGAGGCAGTGCTTACCCCATCAAGGAAGAAGACCTGTTTTTGGCAGTCGGCAAGTCG
CCGGAAGTGGCTGGCGCCATGGCGCAGCATCTGCGCGAACAACGCCAGCTCGACGAAATCACCAGCAGGTTGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References