93714

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3105735..3107449 Replicon chromosome
Accession NZ_CP026217
Organism Aeromonas sp. ASNIH4

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C2U40_RS14255 Protein ID WP_103828952.1
Coordinates 3106796..3107449 (-) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C2U40_RS14250 Protein ID WP_103828953.1
Coordinates 3105735..3106799 (-) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U40_RS14240 3101816..3102529 - 714 WP_103828955.1 M48 family metallopeptidase -
C2U40_RS14245 3102529..3105660 - 3132 WP_103828954.1 HsdR family type I site-specific deoxyribonuclease -
C2U40_RS14250 3105735..3106799 - 1065 WP_103828953.1 macro domain-containing protein Antitoxin
C2U40_RS14255 3106796..3107449 - 654 WP_103828952.1 DUF4433 domain-containing protein Toxin
C2U40_RS14260 3107947..3109224 - 1278 WP_103829203.1 restriction endonuclease subunit S -
C2U40_RS14265 3109224..3111671 - 2448 WP_103829202.1 type I restriction-modification system subunit M -
C2U40_RS14270 3111857..3112303 - 447 WP_103829201.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25233.82 Da        Isoelectric Point: 6.6553

>T93714 WP_103828952.1 NZ_CP026217:c3107449-3106796 [Aeromonas sp. ASNIH4]
MAYDYSQSLNPEKALIFRIVHRDNLEWILTHGLWAGNGLQQSPHWVHIGLPELIAKRARHPVPLVPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPQRDNDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYADLGDLGRIDWPLLQRRDFKRDAEDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNSVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

>T93714 NZ_CP026217:c3107449-3106796 [Aeromonas sp. ASNIH4]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGGAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCTGCAGCAAAGCCCGCACTGGGTGCATATCGGGTTGCCGGAGCTGA
TTGCCAAGCGCGCGCGTCATCCGGTGCCGCTGGTGCCTTACGGCGTGTTGAATGACTATGTACCCTTCTACTTCACGCCG
TTTTCTCCCATGCTCAGCAATATTCACTCAGGGCGAGGTGTTCCCCAGCGTGACAATGATGAAATCTTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAACTGGGGTTGCCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGCCGACCTTGGCGATCTGGGGCGGATTGACTGGCCACTGTTGCAGCGCCGTGATTTCAAGCGTGATGCGGAAGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCGTTGCTGGGCGTGGTGTGTTA
CAACGAAGAGATAAAGAACAGCGTGGAACAGTGCATGAATCGGGTCGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39597.71 Da        Isoelectric Point: 6.6471

>AT93714 WP_103828953.1 NZ_CP026217:c3106799-3105735 [Aeromonas sp. ASNIH4]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSSQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLHTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp

>AT93714 NZ_CP026217:c3106799-3105735 [Aeromonas sp. ASNIH4]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGTTGAAGCGCTGGTGAATACCGTCAACACCGTCGGTGTCAT
GGGCAAGGGGATCGCCTTGATGTTCAAGGAGCGGTTCCCGGCCAATATGCGCGCCTATGCCGAGGCGTGCAAACAGGGTG
ATGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTGGGGCCGCGCTGGATCGTGAATTTTCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGATGGTTTGCAGGATCTGCGGGCCTGGTTACAGGCGCAGCA
GGTCTCTTCGATTGCCATTCCGCCGCTGGGGGCTGGCAACGGTGGTCTGCCTTGGCCAGAGGTCAAACAGGCGATTGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTAGCCAATACCAAAATGTGGCCAAGCGGGGCGGG
GTGGCGGAGCTGACTCCGGCTCGGGCCCTGATTGCTGAACTGGTACGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAGATCCAGAAACTAGCCTGGTTTCTGGCGCGGGTCATTGGCCGCAACCCGCTGGGGGATCCGTTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACCCATCTGCTCAATGCGATGGACGGCAGTTATCTGCAGTCC
GACAAGCGCATCCCGGATAGCAAGCCGTTTGATGTCATCTGGTTTAATGAGGCCAAAAAACAAGAGCTTGCCGTTTATCT
CCATACCGAGGCCAAAGCATTTTTACCGATACTGGAGCAGACGACCGCGTTAATCGACGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTCGATTGGTTGATAGCCGAAGAGGGCTGTGCGCCGACGCTGAGCGCGCTGCGAGAGGGGTTG
CATCGCTGGCCAGCGGGAACCCCGTGGGGTGAGCGCAAGGCGCGGCTGTTTGATGATCGTAGTCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGATTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References