Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4973834..4973979 Replicon chromosome
Accession NZ_CP026177
Organism Klebsiella pneumoniae strain KPNIH50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4973870..4973972 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4973834..4973979 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U50_RS29395 4968964..4971024 + 2061 WP_004151449.1 oligopeptidase B -
C2U50_RS29400 4971028..4971687 - 660 WP_021440386.1 exodeoxyribonuclease X -
C2U50_RS29405 4971766..4971996 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2U50_RS29410 4972109..4972483 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2U50_RS29415 4972487..4973356 + 870 WP_064172307.1 copper homeostasis membrane protein CopD -
C2U50_RS29420 4973373..4973711 + 339 WP_002911404.1 YebY family protein -
- 4973834..4973979 - 146 - - Antitoxin
- 4973870..4973972 + 103 - - Toxin
C2U50_RS33000 4974346..4974489 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2U50_RS29430 4974594..4975562 - 969 WP_004151446.1 VirK/YbjX family protein -
C2U50_RS29435 4975719..4976372 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
C2U50_RS29440 4976369..4976560 - 192 WP_002911395.1 YebW family protein -
C2U50_RS29445 4976658..4976897 - 240 WP_002911393.1 YebV family protein -
C2U50_RS29450 4977013..4978446 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93646 NZ_CP026177:4973870-4973972 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93646 NZ_CP026177:c4973979-4973834 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References