Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1948695..1948840 Replicon chromosome
Accession NZ_CP026162
Organism Klebsiella pneumoniae strain F13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1948731..1948833 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1948695..1948840 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2M13_RS09595 1943825..1945885 + 2061 WP_004151449.1 oligopeptidase B -
C2M13_RS09600 1945889..1946548 - 660 WP_021440386.1 exodeoxyribonuclease X -
C2M13_RS09605 1946627..1946857 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2M13_RS09610 1946970..1947344 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2M13_RS09615 1947348..1948217 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
C2M13_RS09620 1948234..1948572 + 339 WP_002911404.1 YebY family protein -
- 1948695..1948840 - 146 - - Antitoxin
- 1948731..1948833 + 103 - - Toxin
C2M13_RS27695 1949208..1949351 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2M13_RS09630 1949456..1950424 - 969 WP_004151446.1 VirK/YbjX family protein -
C2M13_RS09635 1950581..1951234 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
C2M13_RS09640 1951231..1951422 - 192 WP_002911395.1 YebW family protein -
C2M13_RS09645 1951520..1951759 - 240 WP_002911393.1 YebV family protein -
C2M13_RS09650 1951875..1953308 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93591 NZ_CP026162:1948731-1948833 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93591 NZ_CP026162:c1948840-1948695 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References