Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910205..1910350 Replicon chromosome
Accession NZ_CP026160
Organism Klebsiella pneumoniae strain F93-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910241..1910343 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910205..1910350 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2M21_RS09595 1905335..1907395 + 2061 WP_004151449.1 oligopeptidase B -
C2M21_RS09600 1907399..1908058 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2M21_RS09605 1908137..1908367 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2M21_RS09610 1908480..1908854 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2M21_RS09615 1908858..1909727 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
C2M21_RS09620 1909744..1910082 + 339 WP_048982383.1 YebY family protein -
- 1910205..1910350 - 146 - - Antitoxin
- 1910241..1910343 + 103 - - Toxin
C2M21_RS27035 1910719..1910862 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2M21_RS09630 1910967..1911935 - 969 WP_004151446.1 VirK/YbjX family protein -
C2M21_RS09635 1912092..1912745 + 654 WP_048982385.1 protein-serine/threonine phosphatase -
C2M21_RS09640 1912742..1912933 - 192 WP_002911395.1 YebW family protein -
C2M21_RS09645 1913031..1913270 - 240 WP_002911393.1 YebV family protein -
C2M21_RS09650 1913386..1914819 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93571 NZ_CP026160:1910241-1910343 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93571 NZ_CP026160:c1910350-1910205 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References