Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1853536..1853681 Replicon chromosome
Accession NZ_CP026159
Organism Klebsiella pneumoniae strain F89-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1853572..1853674 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1853536..1853681 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2M18_RS09190 1848666..1850726 + 2061 WP_004151449.1 oligopeptidase B -
C2M18_RS09195 1850730..1851389 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2M18_RS09200 1851468..1851698 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2M18_RS09205 1851811..1852185 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2M18_RS09210 1852189..1853058 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
C2M18_RS09215 1853075..1853413 + 339 WP_002911404.1 YebY family protein -
- 1853536..1853681 - 146 - - Antitoxin
- 1853572..1853674 + 103 - - Toxin
C2M18_RS26585 1854049..1854192 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2M18_RS09225 1854297..1855265 - 969 WP_014907334.1 VirK/YbjX family protein -
C2M18_RS09230 1855422..1856075 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
C2M18_RS09235 1856072..1856263 - 192 WP_002911395.1 YebW family protein -
C2M18_RS09240 1856361..1856600 - 240 WP_002911393.1 YebV family protein -
C2M18_RS09245 1856716..1858149 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93553 NZ_CP026159:1853572-1853674 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93553 NZ_CP026159:c1853681-1853536 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References