Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1879115..1879260 Replicon chromosome
Accession NZ_CP026157
Organism Klebsiella pneumoniae strain F93-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1879151..1879253 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1879115..1879260 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2M12_RS09330 1874245..1876305 + 2061 WP_004151449.1 oligopeptidase B -
C2M12_RS09335 1876309..1876968 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2M12_RS09340 1877047..1877277 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2M12_RS09345 1877390..1877764 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2M12_RS09350 1877768..1878637 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
C2M12_RS09355 1878654..1878992 + 339 WP_002911404.1 YebY family protein -
- 1879115..1879260 - 146 - - Antitoxin
- 1879151..1879253 + 103 - - Toxin
C2M12_RS26215 1879628..1879771 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2M12_RS09365 1879876..1880844 - 969 WP_074195444.1 DUF535 family protein -
C2M12_RS09370 1881001..1881654 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C2M12_RS09375 1881651..1881842 - 192 WP_002911395.1 YebW family protein -
C2M12_RS09380 1881940..1882179 - 240 WP_002911393.1 YebV family protein -
C2M12_RS09385 1882295..1883728 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93531 NZ_CP026157:1879151-1879253 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93531 NZ_CP026157:c1879260-1879115 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References