Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2003383..2003528 Replicon chromosome
Accession NZ_CP026145
Organism Klebsiella pneumoniae strain F132

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2003419..2003521 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2003383..2003528 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2M08_RS10065 1998513..2000573 + 2061 WP_004151449.1 oligopeptidase B -
C2M08_RS10070 2000577..2001236 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2M08_RS10075 2001315..2001545 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2M08_RS10080 2001658..2002032 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2M08_RS10085 2002036..2002905 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
C2M08_RS10090 2002922..2003260 + 339 WP_002911404.1 YebY family protein -
- 2003383..2003528 - 146 - - Antitoxin
- 2003419..2003521 + 103 - - Toxin
C2M08_RS29780 2003896..2004039 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2M08_RS10100 2004144..2005112 - 969 WP_004151446.1 VirK/YbjX family protein -
C2M08_RS10105 2005269..2005922 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C2M08_RS10110 2005919..2006110 - 192 WP_002911395.1 YebW family protein -
C2M08_RS10115 2006208..2006447 - 240 WP_002911393.1 YebV family protein -
C2M08_RS10120 2006563..2007996 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93466 NZ_CP026145:2003419-2003521 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93466 NZ_CP026145:c2003528-2003383 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References