Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013263..2013408 Replicon chromosome
Accession NZ_CP026140
Organism Klebsiella pneumoniae strain F127

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013299..2013401 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013263..2013408 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2L73_RS10120 2008393..2010453 + 2061 WP_004151449.1 oligopeptidase B -
C2L73_RS10125 2010457..2011116 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2L73_RS10130 2011195..2011425 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2L73_RS10135 2011538..2011912 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2L73_RS10140 2011916..2012785 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
C2L73_RS10145 2012802..2013140 + 339 WP_002911404.1 YebY family protein -
- 2013263..2013408 - 146 - - Antitoxin
- 2013299..2013401 + 103 - - Toxin
C2L73_RS29750 2013776..2013919 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2L73_RS10155 2014024..2014992 - 969 WP_004151446.1 VirK/YbjX family protein -
C2L73_RS10160 2015149..2015802 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C2L73_RS10165 2015799..2015990 - 192 WP_002911395.1 YebW family protein -
C2L73_RS10170 2016088..2016327 - 240 WP_002911393.1 YebV family protein -
C2L73_RS10175 2016443..2017876 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93438 NZ_CP026140:2013299-2013401 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93438 NZ_CP026140:c2013408-2013263 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References