Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019508..2019653 Replicon chromosome
Accession NZ_CP026132
Organism Klebsiella pneumoniae strain F5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019544..2019646 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019508..2019653 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2L61_RS10145 2014638..2016698 + 2061 WP_004151449.1 oligopeptidase B -
C2L61_RS10150 2016702..2017361 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2L61_RS10155 2017440..2017670 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2L61_RS10160 2017783..2018157 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2L61_RS10165 2018161..2019030 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
C2L61_RS10170 2019047..2019385 + 339 WP_002911404.1 YebY family protein -
- 2019508..2019653 - 146 - - Antitoxin
- 2019544..2019646 + 103 - - Toxin
C2L61_RS30625 2020021..2020164 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2L61_RS10180 2020269..2021237 - 969 WP_004151446.1 VirK/YbjX family protein -
C2L61_RS10185 2021394..2022047 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C2L61_RS10190 2022044..2022235 - 192 WP_002911395.1 YebW family protein -
C2L61_RS10195 2022333..2022572 - 240 WP_002911393.1 YebV family protein -
C2L61_RS10200 2022688..2024121 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T93392 NZ_CP026132:2019544-2019646 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT93392 NZ_CP026132:c2019653-2019508 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References