Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2019385..2019530 | Replicon | chromosome |
| Accession | NZ_CP026130 | ||
| Organism | Klebsiella pneumoniae strain F1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2019421..2019523 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2019385..2019530 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C2L60_RS10225 | 2014515..2016575 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| C2L60_RS10230 | 2016579..2017238 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| C2L60_RS10235 | 2017317..2017547 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| C2L60_RS10240 | 2017660..2018034 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| C2L60_RS10245 | 2018038..2018907 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| C2L60_RS10250 | 2018924..2019262 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2019385..2019530 | - | 146 | - | - | Antitoxin |
| - | 2019421..2019523 | + | 103 | - | - | Toxin |
| C2L60_RS29575 | 2019898..2020041 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| C2L60_RS10260 | 2020146..2021114 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| C2L60_RS10265 | 2021271..2021924 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| C2L60_RS10270 | 2021921..2022112 | - | 192 | WP_002911395.1 | YebW family protein | - |
| C2L60_RS10275 | 2022210..2022449 | - | 240 | WP_002911393.1 | YebV family protein | - |
| C2L60_RS10280 | 2022565..2023998 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T93365 NZ_CP026130:2019421-2019523 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT93365 NZ_CP026130:c2019530-2019385 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
