Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4091080..4091750 Replicon chromosome
Accession NZ_CP026124
Organism Achromobacter sp. AONIH1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C2U31_RS18810 Protein ID WP_103274163.1
Coordinates 4091080..4091499 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C2U31_RS18815 Protein ID WP_103274164.1
Coordinates 4091496..4091750 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U31_RS18785 4086745..4087611 - 867 WP_158658402.1 hypothetical protein -
C2U31_RS18790 4087929..4088186 + 258 WP_103276445.1 hypothetical protein -
C2U31_RS18795 4088173..4088859 - 687 WP_103276446.1 class I SAM-dependent methyltransferase -
C2U31_RS18800 4089086..4089493 - 408 WP_103274161.1 DoxX family protein -
C2U31_RS18805 4089665..4091053 - 1389 WP_103274162.1 ATP-dependent RNA helicase DbpA -
C2U31_RS18810 4091080..4091499 - 420 WP_103274163.1 PIN domain-containing protein Toxin
C2U31_RS18815 4091496..4091750 - 255 WP_103274164.1 plasmid stabilization protein Antitoxin
C2U31_RS18820 4091855..4092628 - 774 WP_103274165.1 IclR family transcriptional regulator -
C2U31_RS18825 4092800..4094611 + 1812 WP_103274166.1 sulfoacetaldehyde acetyltransferase -
C2U31_RS18830 4094778..4095698 + 921 WP_103274167.1 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase -
C2U31_RS18835 4095711..4096583 - 873 WP_199770851.1 DUF4240 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14612.89 Da        Isoelectric Point: 6.2212

>T93353 WP_103274163.1 NZ_CP026124:c4091499-4091080 [Achromobacter sp. AONIH1]
MIVLDTNVVSEAMKPEPHPAVKTWLNDQVAETLYLSSVTLAEMMYGIGALPEGRRKRGLGMVFDGIVALFGERVLAFDAD
AAHHYAALAIKARAAGKGLPMADGYIAAIAAARGYAVATRDAAPFQAAGIAVINPWDAS

Download         Length: 420 bp

>T93353 NZ_CP026124:c4091499-4091080 [Achromobacter sp. AONIH1]
ATGATCGTCCTGGACACCAACGTCGTCTCCGAAGCGATGAAGCCCGAGCCGCATCCGGCGGTCAAGACCTGGTTGAACGA
CCAGGTGGCCGAGACCCTGTACCTGTCCAGCGTCACGCTCGCCGAGATGATGTACGGCATCGGCGCCCTGCCCGAAGGCC
GGCGCAAGCGCGGCCTGGGCATGGTCTTCGACGGCATCGTCGCGCTGTTCGGCGAGCGCGTGCTGGCCTTCGACGCCGAC
GCCGCCCATCACTACGCGGCGCTGGCCATCAAGGCGCGCGCCGCCGGCAAGGGCCTGCCAATGGCGGACGGTTATATTGC
CGCCATCGCCGCCGCCCGGGGATACGCCGTCGCCACCCGCGACGCCGCGCCCTTCCAGGCAGCGGGCATTGCCGTCATCA
ATCCCTGGGACGCGTCCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9487.93 Da        Isoelectric Point: 10.5729

>AT93353 WP_103274164.1 NZ_CP026124:c4091750-4091496 [Achromobacter sp. AONIH1]
MAILTVRNVPDEVHRALRLRAANHGRSTEAEVREILEHAVKAEQRPRLGDLLAELGRKAGLRNEDFAVLEDTRDRKPAKP
MKIA

Download         Length: 255 bp

>AT93353 NZ_CP026124:c4091750-4091496 [Achromobacter sp. AONIH1]
ATGGCGATCCTGACCGTCCGAAACGTGCCCGACGAAGTCCACCGCGCCCTGCGCCTGCGCGCGGCCAACCACGGCCGCAG
CACCGAGGCCGAAGTGCGCGAGATCCTGGAACACGCGGTGAAGGCCGAGCAGCGCCCGCGCCTGGGCGACCTGCTGGCGG
AACTCGGCCGCAAGGCCGGCCTGCGCAACGAGGACTTCGCCGTCCTGGAAGACACGCGCGACCGCAAACCCGCCAAGCCG
ATGAAAATCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References