Detailed information of TA system TA093352

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 3833193..3833866
• Replicon: chromosome
• Accession: NZ_CP026124
• Organism: Achromobacter sp. AONIH1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: C2U31_RS17610
• Protein ID: WP_103273945.1
• Coordinates: 3833193..3833615 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: C2U31_RS17615
• Protein ID: WP_103273946.1
• Coordinates: 3833612..3833866 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2U31_RS17600	3829108..3831699	+	2592	WP_103273943.1	type II secretion system secretin GspD	-
C2U31_RS17605	3831734..3833161	+	1428	WP_103273944.1	type II secretion system ATPase GspE	-
C2U31_RS17610	3833193..3833615	-	423	WP_103273945.1	type II toxin-antitoxin system VapC family toxin	Toxin
C2U31_RS17615	3833612..3833866	-	255	WP_103273946.1	plasmid stabilization protein	Antitoxin
C2U31_RS17620	3834053..3835561	-	1509	WP_103273947.1	purine permease	-
C2U31_RS17625	3835731..3836960	-	1230	WP_103273948.1	ArgE/DapE family deacylase	-
C2U31_RS17630	3836978..3838756	-	1779	WP_103273949.1	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 15119.62 Da
• Isoelectric Point: 5.6375

>T93352 WP_103273945.1 NZ_CP026124:c3833615-3833193 [Achromobacter sp. AONIH1]
MILLDTNVISEPLRPSPEIRVIDWIDAQPLETLYLSAITVAELRAGIALMPAGKRRTALHEHIEKRVLPMFAGRVLPFDM
ACTNAYAELITKVREAGSGIQTADACIAAVALANGFAVATRDTSPFLAAGLDVIDPWKHA

Nucleotide

• Length: 423 bp

>T93352 NZ_CP026124:c3833615-3833193 [Achromobacter sp. AONIH1]
ATGATCCTGCTCGATACGAACGTCATTTCGGAACCGCTGCGCCCCTCGCCCGAGATTCGTGTCATTGATTGGATAGACGC
GCAGCCGCTGGAAACGTTGTACCTGTCAGCCATCACTGTCGCCGAACTGCGTGCGGGCATCGCGCTGATGCCCGCAGGCA
AGCGCCGTACCGCGCTGCACGAGCACATCGAAAAACGCGTATTGCCGATGTTTGCCGGGCGCGTCCTGCCGTTCGATATG
GCCTGCACGAATGCCTACGCCGAACTGATAACAAAGGTGCGCGAGGCAGGAAGCGGTATCCAGACCGCCGACGCCTGCAT
CGCGGCGGTGGCGCTTGCCAACGGATTTGCCGTTGCCACGCGCGACACCAGCCCCTTCCTGGCCGCCGGCCTGGACGTTA
TTGATCCTTGGAAGCACGCGTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9228.48 Da
• Isoelectric Point: 6.8810

>AT93352 WP_103273946.1 NZ_CP026124:c3833866-3833612 [Achromobacter sp. AONIH1]
MPSVTIRNVPDEVHRAIRVRAAQHGHSIEAEMRDILESAVKPAGRVKLGSLLSEIGRKVKLTEEELALFDSGHDQAQARA
ASFE

Nucleotide

• Length: 255 bp

>AT93352 NZ_CP026124:c3833866-3833612 [Achromobacter sp. AONIH1]
ATGCCATCCGTGACCATCCGTAATGTACCGGACGAGGTGCATCGCGCCATCCGCGTGCGAGCCGCTCAACACGGGCACAG
CATCGAAGCGGAAATGCGAGACATCCTGGAAAGCGCTGTAAAGCCGGCTGGCCGGGTCAAGTTGGGTTCCCTGCTGTCCG
AGATCGGACGCAAGGTCAAACTGACCGAAGAAGAGCTCGCCCTTTTCGACAGCGGGCACGACCAGGCGCAAGCCCGAGCA
GCGAGTTTTGAATGA