Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/PRK09812-MazE
Location 1498397..1498989 Replicon chromosome
Accession NZ_CP026124
Organism Achromobacter sp. AONIH1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag C2U31_RS06910 Protein ID WP_103272166.1
Coordinates 1498397..1498744 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag C2U31_RS06915 Protein ID WP_103272167.1
Coordinates 1498744..1498989 (-) Length 82 a.a.

Genomic Context

C2U31_RS06890C2U31_RS06900C2U31_RS06895C2U31_RS06905C2U31_RS06910C2U31_RS06915C2U31_RS06920C2U31_RS06925C2U31_RS06930C2U31_RS06935
Location: 1494317..1495150 (834 bp)
Type: Others
Protein ID: WP_103272163.1
Location: 1496413..1497267 (855 bp)
Type: Others
Protein ID: WP_103272164.1
Location: 1495217..1496251 (1035 bp)
Type: Others
Protein ID: WP_103276291.1
Location: 1497372..1498355 (984 bp)
Type: Others
Protein ID: WP_103272165.1
Location: 1498397..1498744 (348 bp)
Type: Toxin
Protein ID: WP_103272166.1
Location: 1498744..1498989 (246 bp)
Type: Antitoxin
Protein ID: WP_103272167.1
Location: 1499212..1500342 (1131 bp)
Type: Others
Protein ID: WP_103272168.1
Location: 1500380..1501285 (906 bp)
Type: Others
Protein ID: WP_103272169.1
Location: 1501295..1502305 (1011 bp)
Type: Others
Protein ID: WP_103272170.1
Location: 1502302..1503285 (984 bp)
Type: Others
Protein ID: WP_103272171.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C2U31_RS068901494317..1495150+834WP_103272163.1AraC family transcriptional regulator-
C2U31_RS068951495217..1496251-1035WP_103276291.1low specificity L-threonine aldolase-
C2U31_RS069001496413..1497267+855WP_103272164.1class II glutamine amidotransferase-
C2U31_RS069051497372..1498355-984WP_103272165.12,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase-
C2U31_RS069101498397..1498744-348WP_103272166.1type II toxin-antitoxin system PemK/MazF family toxinToxin
C2U31_RS069151498744..1498989-246WP_103272167.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
C2U31_RS069201499212..1500342-1131WP_103272168.1M20 family metallopeptidase-
C2U31_RS069251500380..1501285-906WP_103272169.1prolyl oligopeptidase family serine peptidase-
C2U31_RS069301501295..1502305-1011WP_103272170.1ABC transporter ATP-binding protein-
C2U31_RS069351502302..1503285-984WP_103272171.1ABC transporter ATP-binding protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-113)

Antitoxin

SpoVT-AbrB domain

(6-50)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12720.61 Da        Isoelectric Point: 7.9698

>T93350 WP_103272166.1 NZ_CP026124:c1498744-1498397 [Achromobacter sp. AONIH1]
MAYVPSHGDIVHLQFDPAAGREMTGPHYGLVVSHKEFNQLGLAMICPISQGQATEQRTHGTVVTLMGTGTATTGSIHCHQ
LKSLDWRVRQAKRKESVPAYLVDEVWARLEAIMRP

Download         Length: 348 bp

>T93350 NZ_CP026124:c1498744-1498397 [Achromobacter sp. AONIH1]
ATGGCATACGTGCCCAGCCACGGCGATATCGTGCATCTACAGTTTGATCCCGCTGCCGGCAGGGAAATGACGGGTCCGCA
CTACGGACTAGTCGTCAGCCACAAGGAGTTCAATCAACTTGGACTGGCGATGATCTGTCCGATTTCACAAGGTCAGGCCA
CCGAACAACGCACTCATGGCACGGTGGTCACGCTGATGGGCACGGGGACCGCGACGACGGGCAGCATCCATTGCCATCAA
CTGAAATCACTGGATTGGCGCGTGCGGCAGGCCAAACGAAAAGAGTCAGTGCCCGCGTACCTCGTCGATGAAGTCTGGGC
TCGGCTTGAAGCGATAATGCGTCCTTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9045.37 Da        Isoelectric Point: 8.6193

>AT93350 WP_103272167.1 NZ_CP026124:c1498989-1498744 [Achromobacter sp. AONIH1]
MRQTLRKAGGSLVMTIPKAYIDQNGLREGSQVELHMSGRRLTIEPPARPRYALTDLLAEMPDGLPRADGWDDMPAVGRER
N

Download         Length: 246 bp

>AT93350 NZ_CP026124:c1498989-1498744 [Achromobacter sp. AONIH1]
ATGCGTCAAACTCTACGCAAGGCAGGAGGTTCGCTCGTGATGACCATCCCCAAGGCATACATCGACCAGAACGGGCTGCG
TGAAGGCTCCCAGGTCGAACTCCACATGTCCGGCCGGCGGCTCACTATCGAACCGCCAGCGCGTCCGCGCTATGCGCTCA
CCGACCTCCTGGCTGAAATGCCGGATGGGCTGCCCCGAGCCGACGGCTGGGACGACATGCCCGCTGTCGGACGGGAGCGC
AACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References