Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1359506..1360149 Replicon chromosome
Accession NZ_CP026124
Organism Achromobacter sp. AONIH1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C2U31_RS06305 Protein ID WP_103272060.1
Coordinates 1359739..1360149 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C2U31_RS06300 Protein ID WP_103272059.1
Coordinates 1359506..1359739 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U31_RS06270 1354886..1355398 + 513 WP_103276279.1 DUF4810 domain-containing protein -
C2U31_RS06275 1355401..1356051 + 651 WP_103272054.1 DUF799 domain-containing protein -
C2U31_RS06280 1356195..1357121 - 927 WP_103272055.1 DMT family transporter -
C2U31_RS06285 1357194..1357742 + 549 WP_103272056.1 XRE family transcriptional regulator -
C2U31_RS06290 1357877..1358362 - 486 WP_103272057.1 GNAT family N-acetyltransferase -
C2U31_RS06295 1358484..1359398 + 915 WP_103272058.1 LysR family transcriptional regulator -
C2U31_RS06300 1359506..1359739 + 234 WP_103272059.1 antitoxin Antitoxin
C2U31_RS06305 1359739..1360149 + 411 WP_103272060.1 type II toxin-antitoxin system VapC family toxin Toxin
C2U31_RS06310 1360207..1362084 - 1878 WP_103276280.1 methyl-accepting chemotaxis protein -
C2U31_RS06315 1362329..1364419 - 2091 WP_103272061.1 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14896.09 Da        Isoelectric Point: 6.8709

>T93349 WP_103272060.1 NZ_CP026124:1359739-1360149 [Achromobacter sp. AONIH1]
MLRYLLDTNIVIYVLKRRPIEVLSIFNANAGRMAISSITAAELLHGAEKSNRVSENLSTVEDFCSRLDVLPYGLKAAQHY
GAIRSALERLGQPIGVNDLHIAGHARSEGLVLVSNNVSEFARVPGLEVENWVSPSL

Download         Length: 411 bp

>T93349 NZ_CP026124:1359739-1360149 [Achromobacter sp. AONIH1]
ATGCTGCGCTATCTGCTGGACACGAACATCGTTATCTATGTCTTGAAGCGGCGTCCCATCGAGGTGCTGTCCATTTTCAA
TGCCAATGCGGGCCGCATGGCGATCTCCTCGATTACCGCGGCGGAGCTGTTGCATGGCGCGGAGAAAAGCAACCGTGTCA
GTGAGAACCTGTCCACCGTTGAGGATTTTTGCAGCCGCCTGGATGTCTTGCCCTATGGCCTCAAAGCGGCGCAGCACTAC
GGGGCGATCCGTTCCGCCCTGGAACGGCTGGGTCAGCCCATTGGGGTAAACGATCTGCACATCGCAGGCCATGCACGTAG
TGAAGGCTTGGTGCTGGTATCGAACAACGTATCGGAATTCGCCCGCGTTCCCGGGCTTGAAGTAGAGAACTGGGTCAGTC
CCAGCCTCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8654.87 Da        Isoelectric Point: 4.7063

>AT93349 WP_103272059.1 NZ_CP026124:1359506-1359739 [Achromobacter sp. AONIH1]
MAIGTVFINNRTQAVRLPLEVRLPEGVLKVEIRVRGNERIIAPVGQIWDSFFLNGPAVSDDFMSERASQDQAERESL

Download         Length: 234 bp

>AT93349 NZ_CP026124:1359506-1359739 [Achromobacter sp. AONIH1]
ATGGCAATTGGCACGGTCTTTATCAACAACCGCACGCAGGCCGTCCGGCTTCCGCTGGAAGTCCGGCTGCCAGAGGGCGT
GCTCAAGGTGGAAATACGAGTCAGGGGAAATGAGCGCATCATTGCGCCGGTTGGACAGATCTGGGACAGCTTTTTTCTGA
ACGGCCCCGCTGTCAGCGATGATTTCATGTCCGAACGTGCCAGCCAGGATCAAGCCGAGCGAGAGTCGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References