Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 322919..323456 Replicon chromosome
Accession NZ_CP026124
Organism Achromobacter sp. AONIH1

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag C2U31_RS01430 Protein ID WP_103271232.1
Coordinates 322919..323218 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C2U31_RS01435 Protein ID WP_103271233.1
Coordinates 323208..323456 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U31_RS01410 318769..319149 - 381 WP_103271229.1 hypothetical protein -
C2U31_RS01415 319164..320573 - 1410 WP_103271230.1 DKNYY domain-containing protein -
C2U31_RS01420 320768..322159 + 1392 WP_103271231.1 uracil-xanthine permease family protein -
C2U31_RS01430 322919..323218 - 300 WP_103271232.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C2U31_RS01435 323208..323456 - 249 WP_103271233.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C2U31_RS30405 323513..323884 - 372 WP_158658286.1 hypothetical protein -
C2U31_RS01440 324079..324360 + 282 WP_103271234.1 type II toxin-antitoxin system HigB family toxin -
C2U31_RS01445 324348..324797 + 450 WP_103271235.1 transcriptional regulator -
C2U31_RS01450 324944..325960 + 1017 WP_103271236.1 amino acid ABC transporter substrate-binding protein -
C2U31_RS01455 326142..326423 + 282 WP_103271237.1 peptidylprolyl isomerase -
C2U31_RS01460 326491..327135 - 645 WP_103271238.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-77)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11359.17 Da        Isoelectric Point: 10.8542

>T93347 WP_103271232.1 NZ_CP026124:c323218-322919 [Achromobacter sp. AONIH1]
MSFDLGFLDEALKEWRKLDRNTREQFKAKLAERLTNPRVPAAKLGGHKDRYKIKLRSAGYRLVYEVRDRELIVVVVAVGK
RERNAVYTAAAKRQALGDG

Download         Length: 300 bp

>T93347 NZ_CP026124:c323218-322919 [Achromobacter sp. AONIH1]
ATGAGCTTTGATCTCGGGTTCCTCGACGAGGCGCTCAAGGAATGGCGCAAGCTCGACCGCAACACGCGGGAGCAATTCAA
GGCCAAACTGGCCGAGCGCCTGACCAACCCGCGCGTACCGGCCGCCAAGCTCGGCGGCCACAAGGACCGCTACAAGATCA
AGCTGCGCAGCGCCGGTTATCGCCTGGTGTATGAGGTGCGCGACCGTGAGCTGATCGTCGTGGTGGTCGCAGTCGGCAAA
CGCGAGCGCAATGCCGTTTACACGGCGGCAGCCAAGCGACAGGCCCTCGGGGATGGATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8844.29 Da        Isoelectric Point: 4.7185

>AT93347 WP_103271233.1 NZ_CP026124:c323456-323208 [Achromobacter sp. AONIH1]
MSHLILAEITASVSELKKNPMGTVAAGEGFPVAILNRNAPAFYCVPAKAYEALMERLEDMELNALADARQGQAVVKVKLD
EL

Download         Length: 249 bp

>AT93347 NZ_CP026124:c323456-323208 [Achromobacter sp. AONIH1]
ATGTCGCATCTTATTTTGGCGGAAATCACCGCGAGCGTGTCAGAACTCAAGAAGAATCCGATGGGTACTGTCGCCGCAGG
CGAAGGCTTCCCGGTTGCCATCCTGAACCGGAATGCCCCAGCGTTTTACTGCGTGCCGGCGAAGGCGTATGAAGCGCTGA
TGGAGCGGCTTGAAGATATGGAATTGAACGCCCTGGCCGACGCGCGGCAAGGTCAGGCCGTTGTTAAGGTCAAGCTCGAT
GAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References