Detailed information of TA system TA093343

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 3932829..3933345
• Replicon: chromosome
• Accession: NZ_CP026115
• Organism: Pseudomonas putida strain W5

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C2H86_RS17950
• Protein ID: WP_159409185.1
• Coordinates: 3933058..3933345 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C2H86_RS17945
• Protein ID: WP_103449480.1
• Coordinates: 3932829..3933068 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2H86_RS17930	3928708..3929592	+	885	WP_159409182.1	hypothetical protein	-
C2H86_RS17935	3929661..3931121	-	1461	WP_159409183.1	PLP-dependent aminotransferase family protein	-
C2H86_RS17940	3931138..3932568	-	1431	WP_159409184.1	L-lactate permease	-
C2H86_RS17945	3932829..3933068	+	240	WP_103449480.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
C2H86_RS17950	3933058..3933345	+	288	WP_159409185.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C2H86_RS17955	3933431..3934681	-	1251	WP_027918055.1	ribonucleotide-diphosphate reductase subunit beta	-
C2H86_RS17960	3934928..3937807	-	2880	WP_159409186.1	ribonucleoside-diphosphate reductase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-81)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-69)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11238.07 Da
• Isoelectric Point: 10.0977

>T93343 WP_159409185.1 NZ_CP026115:3933058-3933345 [Pseudomonas putida]
MTYSLEFDSRALKEWKKLGDTVRQQFKKKLAEVLLSPRVEANRLSSLPDCYKIKLRSSGYRLVYQVIDLEVVVFVVAVDR
RERDQVYRKAAERLE

Nucleotide

• Length: 288 bp

>T93343 NZ_CP026115:3933058-3933345 [Pseudomonas putida]
ATGACCTATAGCCTCGAGTTCGACTCACGCGCGTTGAAAGAATGGAAAAAGCTTGGCGATACGGTTCGTCAGCAGTTCAA
GAAGAAACTGGCCGAGGTTCTGCTGAGCCCGAGAGTGGAGGCCAATCGTCTCAGTTCGCTTCCCGACTGTTACAAGATAA
AGCTGCGCAGTAGTGGCTACCGCTTGGTCTATCAGGTCATTGATCTAGAAGTGGTGGTGTTTGTGGTGGCCGTTGATCGC
CGCGAACGTGACCAGGTTTATCGGAAGGCAGCCGAGCGACTTGAGTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9165.56 Da
• Isoelectric Point: 4.6437

>AT93343 WP_103449480.1 NZ_CP026115:3932829-3933068 [Pseudomonas putida]
MASINIRVDDELKARAYQELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIAIVRERLASPQRVRVQLDDL

Nucleotide

• Length: 240 bp

>AT93343 NZ_CP026115:3932829-3933068 [Pseudomonas putida]
ATGGCGTCCATCAATATCCGCGTCGATGACGAACTCAAGGCTCGTGCATACCAGGAGCTCGAACGACTTGGCGTGACCCC
TTCCGAACTCATGCGCCAAGCGCTGCAATACGTGGCCGAGCGAGGAAAGCTGCCTTTTCGACCCGTCCTGATGACTGAAG
AAGACGAAGACCTGATCGCAATTGTGAGAGAGCGGCTTGCTTCTCCGCAGCGCGTTAGGGTACAGCTGGATGACCTATAG