Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2988880..2989485 Replicon chromosome
Accession NZ_CP026115
Organism Pseudomonas putida strain W5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C2H86_RS13535 Protein ID WP_159412911.1
Coordinates 2988880..2989170 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C2H86_RS13540 Protein ID WP_159412912.1
Coordinates 2989180..2989485 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2H86_RS13515 2984226..2984999 - 774 WP_159412908.1 ABC transporter ATP-binding protein -
C2H86_RS13520 2985644..2987029 + 1386 WP_159412909.1 GABA permease -
C2H86_RS13525 2987214..2987657 - 444 WP_027917576.1 hypothetical protein -
C2H86_RS13530 2987718..2988599 - 882 WP_163986022.1 polyphosphate kinase 2 -
C2H86_RS13535 2988880..2989170 + 291 WP_159412911.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C2H86_RS13540 2989180..2989485 + 306 WP_159412912.1 putative addiction module antidote protein Antitoxin
C2H86_RS13550 2989785..2990057 - 273 WP_159412913.1 oxidative damage protection protein -
C2H86_RS13555 2990054..2991121 - 1068 WP_159412914.1 A/G-specific adenine glycosylase -
C2H86_RS13560 2991118..2993355 - 2238 WP_159412915.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(3-96)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10970.63 Da        Isoelectric Point: 10.6653

>T93341 WP_159412911.1 NZ_CP026115:2988880-2989170 [Pseudomonas putida]
MRTLLQTDSYRRWFAALRDARAQARINVRLRRVELGVTGDCRPVGEGVSELRIDYGPGYRVYFVQRGYEVIILLAGGDKS
TQARDIRSALKLAREL

Download         Length: 291 bp

>T93341 NZ_CP026115:2988880-2989170 [Pseudomonas putida]
ATGCGCACACTATTACAAACCGACAGCTATAGAAGGTGGTTCGCCGCGTTGCGGGATGCTCGTGCACAGGCTCGTATCAA
TGTGCGCTTGCGGCGGGTCGAGCTTGGAGTGACTGGGGACTGTAGGCCGGTAGGTGAAGGAGTGTCCGAGCTGCGGATCG
ATTACGGTCCGGGCTATCGGGTGTATTTCGTTCAGCGAGGCTACGAGGTGATCATCCTTCTGGCGGGTGGCGACAAGTCC
ACTCAGGCCAGGGATATCAGATCAGCCCTCAAGCTGGCACGCGAGCTATAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10810.45 Da        Isoelectric Point: 4.8307

>AT93341 WP_159412912.1 NZ_CP026115:2989180-2989485 [Pseudomonas putida]
MTDTKLTKWDAADHLKTEEDMALYLEACLEENDPVLLAAALGDIARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGLRLHAEVVSPRTAG

Download         Length: 306 bp

>AT93341 NZ_CP026115:2989180-2989485 [Pseudomonas putida]
ATGACTGATACCAAACTGACCAAGTGGGATGCCGCAGATCACCTCAAGACAGAGGAAGACATGGCTCTGTACCTTGAGGC
CTGCCTTGAAGAAAACGATCCGGTGCTGCTTGCTGCTGCCTTGGGCGATATTGCGCGTGCTCGTGGCATGGCGCAACTGG
CGCGTGATACGGGCCTGACTCGCGAAGGGCTATACAAAGCCTTGTCGGCGGAGGGTAACCCTAGCCTGGCGACCATCATG
AAAGTGATGGCGGCACTCGGCCTGAGGCTACATGCCGAGGTGGTATCTCCGCGAACTGCGGGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References