93339

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1514674..1515292 Replicon chromosome
Accession NZ_CP026115
Organism Pseudomonas putida strain W5

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag C2H86_RS07000 Protein ID WP_205524616.1
Coordinates 1514674..1514979 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag C2H86_RS07005 Protein ID WP_159411984.1
Coordinates 1514972..1515292 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2H86_RS06970 1510107..1510832 + 726 WP_060511298.1 LPS export ABC transporter ATP-binding protein -
C2H86_RS06975 1511009..1512502 + 1494 WP_159411979.1 RNA polymerase factor sigma-54 -
C2H86_RS06980 1512581..1512889 + 309 WP_003255135.1 ribosome-associated translation inhibitor RaiA -
C2H86_RS06985 1512902..1513366 + 465 WP_159411980.1 PTS IIA-like nitrogen regulatory protein PtsN -
C2H86_RS06990 1513369..1514223 + 855 WP_159411981.1 RNase adapter RapZ -
C2H86_RS06995 1514244..1514516 + 273 WP_159411982.1 HPr family phosphocarrier protein -
C2H86_RS07000 1514674..1514979 + 306 WP_205524616.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C2H86_RS07005 1514972..1515292 + 321 WP_159411984.1 helix-turn-helix domain-containing protein Antitoxin
C2H86_RS07010 1515323..1516216 - 894 WP_159411985.1 ZIP family metal transporter -
C2H86_RS07015 1516228..1516839 - 612 WP_159411986.1 superoxide dismutase -
C2H86_RS07020 1516841..1517302 - 462 WP_159411987.1 hypothetical protein -
C2H86_RS07025 1517333..1518709 - 1377 WP_159411988.1 class II fumarate hydratase -
C2H86_RS07030 1518702..1519103 - 402 WP_060484655.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-89)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11158.60 Da        Isoelectric Point: 7.9660

>T93339 WP_205524616.1 NZ_CP026115:1514674-1514979 [Pseudomonas putida]
MPEDVQDIFGFALHQAQEGGKHLQAKCLKGFSGAGVLEVVEDHNRSTYRAVYTVTFGSAVYVLHCFQKKSTSGIKTSSHD
LDLIKSRLKLAEAHSRGEKHD

Download         Length: 306 bp

>T93339 NZ_CP026115:1514674-1514979 [Pseudomonas putida]
CTGCCAGAAGATGTTCAGGACATTTTCGGTTTTGCACTGCACCAGGCGCAGGAAGGTGGCAAACATTTGCAGGCAAAGTG
TCTCAAAGGGTTCAGCGGGGCGGGCGTGCTGGAGGTCGTGGAGGACCACAACCGTAGCACCTATCGTGCGGTGTACACGG
TGACATTCGGCTCAGCAGTCTACGTGTTGCATTGCTTCCAGAAAAAATCCACTTCTGGCATCAAGACCTCCAGCCACGAC
CTTGACTTGATCAAGTCACGCCTGAAACTGGCTGAAGCTCACTCTCGAGGAGAGAAACATGATTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11600.60 Da        Isoelectric Point: 9.8520

>AT93339 WP_159411984.1 NZ_CP026115:1514972-1515292 [Pseudomonas putida]
MIEIEEGSGSVYTDLGSENASEMLVKAHLASKICSIIKARHMTQVQASAVLGLPQPKVSDMMRGKFRGISETKMIDCLAR
LGRDVQIVVKAAPRSRREGRVEVIFA

Download         Length: 321 bp

>AT93339 NZ_CP026115:1514972-1515292 [Pseudomonas putida]
ATGATTGAGATCGAAGAAGGCAGCGGCAGCGTCTATACCGACCTTGGCAGTGAAAATGCCAGCGAGATGCTGGTAAAGGC
GCATCTCGCCAGCAAGATATGCAGCATCATCAAGGCCCGTCATATGACCCAGGTGCAAGCATCGGCAGTCCTTGGCCTTC
CCCAACCCAAGGTTTCCGACATGATGCGCGGTAAATTTCGCGGTATCAGTGAAACCAAGATGATCGATTGTCTGGCCCGG
CTTGGCCGCGATGTACAAATCGTAGTGAAAGCCGCCCCTCGCTCCCGCCGAGAAGGTCGGGTGGAAGTCATCTTCGCCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References