Detailed information of TA system TA093329

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-TIGR02293
• Location: 338724..339736
• Replicon: chromosome
• Accession: NZ_CP026109
• Organism: Paraburkholderia hospita strain DSM 17164

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: C2L64_RS50440
• Protein ID: WP_086917606.1
• Coordinates: 338724..339200 (-)
• Length: 159 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: C2L64_RS50445
• Protein ID: WP_086917607.1
• Coordinates: 339197..339736 (-)
• Length: 180 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2L64_RS50415	334581..335189	-	609	WP_007585009.1	TetR/AcrR family transcriptional regulator	-
C2L64_RS50420	335298..337073	-	1776	WP_086917604.1	alkaline phosphatase D family protein	-
C2L64_RS50425	337194..337514	-	321	WP_086917608.1	antibiotic biosynthesis monooxygenase	-
C2L64_RS50430	337595..337876	-	282	WP_086917605.1	DUF3303 family protein	-
C2L64_RS50440	338724..339200	-	477	WP_086917606.1	RES family NAD+ phosphorylase	Toxin
C2L64_RS50445	339197..339736	-	540	WP_086917607.1	DUF2384 domain-containing protein	Antitoxin
C2L64_RS50450	340404..341921	+	1518	WP_090837084.1	sensor domain-containing diguanylate cyclase	-
C2L64_RS50460	342580..342849	+	270	WP_007741389.1	type II toxin-antitoxin system prevent-host-death family antitoxin	-
C2L64_RS50465	342846..343235	+	390	WP_090837064.1	type II toxin-antitoxin system VapC family toxin	-
C2L64_RS50470	343585..344064	+	480	WP_090837067.1	hypothetical protein	-
C2L64_RS50475	344183..344496	-	314	Protein_330	single-stranded DNA-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-153)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (68-113)

Sequences

Toxin

Protein

• Length: 159 a.a.
• Molecular weight: 17079.65 Da
• Isoelectric Point: 7.8483

>T93329 WP_086917606.1 NZ_CP026109:c339200-338724 [Paraburkholderia hospita]
VTVAVWRIATEAPNYPADDLSGAGAKATGGRWNRRGTPVLYCASTIALACLETVVHIRAAGLPLNRYLVFLDVPDNVWQA
ATVFTNISAPIGWDAIPPGMTSLDTGEKWIYKAATALLLVPSVIVPEETNVLINPAHPDAAGIRAQKVRRWTYDQRMG

Nucleotide

• Length: 477 bp

>T93329 NZ_CP026109:c339200-338724 [Paraburkholderia hospita]
GTGACAGTCGCGGTCTGGCGGATCGCGACCGAAGCGCCCAACTACCCCGCAGACGATCTTTCCGGTGCCGGCGCGAAGGC
GACGGGTGGCCGGTGGAACCGGCGCGGAACGCCGGTTTTGTACTGTGCGTCGACCATCGCCCTGGCCTGTCTGGAAACCG
TGGTTCACATTCGTGCGGCGGGATTGCCGCTGAACCGCTACCTCGTGTTTCTGGACGTGCCCGACAACGTCTGGCAGGCC
GCGACGGTTTTCACGAACATCTCAGCGCCCATAGGATGGGACGCAATCCCGCCCGGTATGACGAGCCTGGATACAGGTGA
GAAATGGATCTATAAGGCTGCCACAGCCCTGCTTCTTGTGCCGTCTGTCATCGTCCCGGAGGAGACGAACGTCCTCATCA
ACCCGGCCCATCCGGATGCCGCGGGCATTCGTGCGCAGAAAGTGCGGCGTTGGACCTACGATCAGCGAATGGGTTAA

Antitoxin

Protein

• Length: 180 a.a.
• Molecular weight: 19398.16 Da
• Isoelectric Point: 10.1681

>AT93329 WP_086917607.1 NZ_CP026109:c339736-339197 [Paraburkholderia hospita]
VNAPATSARRPPARKTAVRVPAKPAAPSRAAKAHATKINDYLTLYHAPPLERISFIKYGVDAYDVYVLARNMGTSQDNLM
VTLGLPRSTIIRKAKGKARLSAEQSERVIGMARLVGQVEAMVAESGNPEGFDAAHWVNEWLDQPNPALDQRRPAEFMDTV
AGQEFVASLLAKAQSGAYA

Nucleotide

• Length: 540 bp

>AT93329 NZ_CP026109:c339736-339197 [Paraburkholderia hospita]
GTGAACGCGCCTGCCACCTCCGCCCGTCGCCCGCCGGCCCGCAAGACTGCAGTTCGTGTCCCGGCAAAACCCGCCGCGCC
GTCGCGGGCTGCCAAAGCGCACGCGACGAAGATCAACGATTACCTCACCCTCTATCACGCGCCTCCGCTCGAGCGCATCA
GCTTCATCAAGTACGGCGTGGATGCCTACGACGTGTACGTTCTTGCGCGCAACATGGGAACCTCGCAGGACAACCTGATG
GTGACCTTGGGGCTGCCGCGCTCGACCATCATCCGTAAGGCCAAGGGGAAGGCGCGTCTGTCCGCGGAGCAGAGCGAACG
GGTGATCGGTATGGCGAGGCTGGTCGGCCAGGTCGAAGCGATGGTCGCCGAATCCGGGAATCCGGAAGGCTTCGACGCCG
CCCACTGGGTAAACGAATGGCTGGACCAGCCCAACCCGGCACTGGATCAGCGCCGTCCTGCTGAGTTCATGGATACGGTC
GCGGGACAGGAATTTGTCGCCTCCCTGCTGGCGAAGGCACAGAGCGGAGCGTACGCGTGA