Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 2770281..2772031 Replicon chromosome
Accession NZ_CP026102
Organism Paraburkholderia caribensis strain DSM 13236

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag C2L66_RS28960 Protein ID WP_054933313.1
Coordinates 2771138..2772031 (-) Length 298 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag C2L66_RS28955 Protein ID WP_054933339.1
Coordinates 2770281..2771141 (-) Length 287 a.a.

Genomic Context

C2L66_RS28990C2L66_RS28935C2L66_RS28940C2L66_RS28945C2L66_RS28950C2L66_RS28955C2L66_RS28960C2L66_RS28965C2L66_RS28970C2L66_RS28975C2L66_RS28980C2L66_RS28985
Location: 2775598..2776671 (1074 bp)
Type: Others
Protein ID: WP_060604756.1
Location: 2765480..2766976 (1497 bp)
Type: Others
Protein ID: WP_060604768.1
Location: 2767001..2767831 (831 bp)
Type: Others
Protein ID: WP_054933316.1
Location: 2767824..2769482 (1659 bp)
Type: Others
Protein ID: WP_060604765.1
Location: 2769475..2770281 (807 bp)
Type: Others
Protein ID: WP_060604762.1
Location: 2770281..2771141 (861 bp)
Type: Antitoxin
Protein ID: WP_054933339.1
Location: 2771138..2772031 (894 bp)
Type: Toxin
Protein ID: WP_054933313.1
Location: 2772057..2772596 (540 bp)
Type: Others
Protein ID: WP_035999007.1
Location: 2772632..2773390 (759 bp)
Type: Others
Protein ID: WP_054933312.1
Location: 2773383..2774471 (1089 bp)
Type: Others
Protein ID: WP_060604759.1
Location: 2774526..2774837 (312 bp)
Type: Others
Protein ID: WP_035999001.1
Location: 2774839..2775156 (318 bp)
Type: Others
Protein ID: WP_035998998.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C2L66_RS289352765480..2766976-1497WP_060604768.1aldehyde dehydrogenase-
C2L66_RS289402767001..2767831-831WP_054933316.1aspartate dehydrogenase-
C2L66_RS289452767824..2769482-1659WP_060604765.1thiamine pyrophosphate-binding protein-
C2L66_RS289502769475..2770281-807WP_060604762.1SDR family oxidoreductase-
C2L66_RS289552770281..2771141-861WP_054933339.1IclR family transcriptional regulatorAntitoxin
C2L66_RS289602771138..2772031-894WP_054933313.1alpha/beta fold hydrolaseToxin
C2L66_RS289652772057..2772596-540WP_035999007.1cupin domain-containing protein-
C2L66_RS289702772632..2773390-759WP_054933312.1SDR family oxidoreductase-
C2L66_RS289752773383..2774471-1089WP_060604759.1aromatic ring-hydroxylating dioxygenase subunit alpha-
C2L66_RS289802774526..2774837-312WP_035999001.1hypothetical protein-
C2L66_RS289852774839..2775156-318WP_035998998.1non-heme iron oxygenase ferredoxin subunit-
C2L66_RS289902775598..2776671+1074WP_060604756.1porin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(50-276)

Antitoxin

Transcription regulator IclR, C-terminal

(144-267)


Sequences

Toxin        


Download         Length: 298 a.a.        Molecular weight: 31101.10 Da        Isoelectric Point: 6.4894

>T93321 WP_054933313.1 NZ_CP026102:c2772031-2771138 [Paraburkholderia caribensis]
MSAALPVTVDRTVTLETRLSHFPARRIAIAPQCAIGYREAGAGHADALPLVLLHGIGSGAASWVQQLDALGTTRRVFAWD
APGYGESTPVASASPKADEYAGALDAWLDALAVERCVLVGHSLGAIIAGSYAASRAQRVAGLLLISPAAGYGTASEDVRA
SKRDSRLAMLAELGPQGLADQRSANMLSPYADEASRDWVRWNMSRIVPTGYAQATHLLANADLASDVARVNGPIAVAVGA
EDSITPPSSCERIAQAARTRLQIIPRAGHAGYIEAANEYTALIDAFCRASDGQWSKA

Download         Length: 894 bp

>T93321 NZ_CP026102:c2772031-2771138 [Paraburkholderia caribensis]
ATGTCCGCAGCCTTGCCCGTCACTGTCGATCGAACCGTCACGCTGGAAACGCGCCTCTCGCACTTCCCGGCACGGCGGAT
CGCGATTGCGCCGCAATGCGCGATCGGCTATCGCGAAGCGGGTGCTGGGCACGCCGATGCGTTGCCGCTCGTGCTGTTGC
ACGGCATTGGTTCGGGCGCGGCTTCGTGGGTGCAACAACTCGACGCGTTGGGCACGACGCGCCGCGTGTTCGCTTGGGAC
GCGCCGGGCTATGGCGAATCGACGCCTGTTGCATCGGCTTCGCCCAAAGCAGATGAATATGCCGGCGCGCTCGACGCATG
GCTCGATGCGCTCGCCGTAGAACGTTGCGTACTGGTCGGCCATTCGCTCGGCGCGATCATCGCGGGCTCGTACGCGGCAT
CGCGTGCGCAACGCGTCGCGGGGCTGTTGCTGATTTCGCCCGCGGCAGGCTACGGCACGGCATCCGAAGACGTGCGCGCG
TCGAAGCGCGACAGCCGTCTCGCGATGCTCGCCGAACTCGGCCCGCAAGGTCTCGCGGACCAACGCAGCGCCAACATGCT
GTCGCCGTACGCCGATGAAGCATCACGCGACTGGGTGCGCTGGAACATGTCGCGCATCGTGCCGACGGGTTACGCGCAGG
CGACGCATCTGCTCGCCAACGCGGATCTCGCCAGCGATGTCGCGAGGGTCAACGGCCCAATCGCCGTCGCGGTCGGGGCG
GAGGACTCGATCACCCCGCCGTCGTCATGCGAGCGGATTGCACAGGCGGCGCGCACGCGCCTGCAGATCATCCCGCGCGC
GGGTCACGCGGGCTACATCGAAGCGGCCAATGAATACACCGCGCTCATCGACGCATTCTGCCGCGCGAGCGACGGTCAAT
GGAGCAAAGCATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31435.86 Da        Isoelectric Point: 6.5093

>AT93321 WP_054933339.1 NZ_CP026102:c2771141-2770281 [Paraburkholderia caribensis]
MTPELTGTAPEAEDDRNDAGYRVPGLERGLRILTEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADRDRN
YRLGVAVLRLGFEYLSSLELTDLGLPLIEALRDATGLTTHIVIRDGRDVVFVAKAQSHAPVFSSVKVNVGTRLPAHATTH
GHVLMGDLSLDELRALYPEKTLERFTKHTPATVDELYERVRDDAVRGFAISESSFENGISVISAPVRNDTGRIAAVITTT
IPRPQIDAALLDGGLIDKVRGAAEQLSLRLNYRPSAESRYMKALGL

Download         Length: 861 bp

>AT93321 NZ_CP026102:c2771141-2770281 [Paraburkholderia caribensis]
ATGACCCCCGAATTGACGGGCACTGCGCCTGAAGCAGAAGACGACCGCAACGACGCGGGCTATCGCGTGCCCGGACTCGA
ACGCGGCCTGCGCATTCTCACGGAGTTCTCGCCGCGCGAACCGGTGCTCGGCGCGCCCGAATTGTCGAAGCGCCTCGGCA
TTCCGCGCACGACGGTGTTCCGTCTGCTGCAGACGCTCGAATCACTGGGCTTTCTGGAGCGCGCGGATCGCGACCGCAAC
TATCGCCTGGGCGTCGCGGTGCTGCGCCTCGGCTTCGAATATCTCAGTTCGCTCGAACTCACCGATCTCGGCTTGCCGTT
GATCGAAGCTTTGCGCGATGCAACGGGGCTGACCACGCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCGA
AGGCGCAGAGTCATGCGCCCGTGTTCAGTTCGGTGAAGGTCAACGTCGGCACGCGGCTACCCGCGCATGCGACTACGCAC
GGTCATGTGCTGATGGGCGATCTCTCGCTCGACGAACTGCGCGCGCTGTATCCGGAGAAGACGCTCGAACGCTTCACGAA
ACACACGCCCGCTACCGTTGACGAACTATACGAGCGCGTGAGGGACGACGCGGTGCGCGGTTTCGCGATCAGCGAATCGT
CCTTCGAAAACGGTATCTCCGTCATCAGTGCGCCCGTGCGCAACGACACGGGCCGCATCGCCGCTGTCATCACCACCACC
ATTCCGCGCCCGCAGATCGACGCGGCGCTGCTCGACGGCGGCCTGATCGACAAGGTGCGCGGCGCGGCGGAGCAATTGTC
GCTGCGGCTGAACTACCGGCCGTCGGCGGAAAGCAGGTACATGAAGGCATTGGGGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References