Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2336263..2336798 Replicon chromosome
Accession NZ_CP026100
Organism Caulobacter flavus strain RHGG3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C1707_RS10880 Protein ID WP_101715777.1
Coordinates 2336263..2336544 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C1707_RS10885 Protein ID WP_101715778.1
Coordinates 2336541..2336798 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1707_RS10855 2331624..2332766 + 1143 WP_101715772.1 cytochrome d ubiquinol oxidase subunit II -
C1707_RS10860 2332787..2332906 + 120 WP_101715773.1 cytochrome bd-I oxidase subunit CydX -
C1707_RS10865 2333022..2333387 + 366 WP_101715774.1 hypothetical protein -
C1707_RS10870 2333399..2334730 - 1332 WP_101715775.1 mannanase -
C1707_RS10875 2334817..2336205 - 1389 WP_101715776.1 alpha/beta fold hydrolase -
C1707_RS10880 2336263..2336544 - 282 WP_101715777.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C1707_RS10885 2336541..2336798 - 258 WP_101715778.1 ribbon-helix-helix protein, CopG family Antitoxin
C1707_RS10890 2336845..2339934 - 3090 WP_101715779.1 bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA -
C1707_RS10895 2340380..2340841 + 462 WP_058348359.1 Lrp/AsnC ligand binding domain-containing protein -
C1707_RS10900 2340938..2341309 + 372 WP_101715780.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Predicted DNA-binding protein, ribbon-helix-helix domain

(7-37)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10568.97 Da        Isoelectric Point: 12.0017

>T93316 WP_101715777.1 NZ_CP026100:c2336544-2336263 [Caulobacter flavus]
VTYKVAVTRRASRDAARLDARLREQNPRAADRLSDQIAQAATSLEESPLRGRAVGATTREINIPFGRSAYIVRYRVRGQH
VTITRIWHGLEQR

Download         Length: 282 bp

>T93316 NZ_CP026100:c2336544-2336263 [Caulobacter flavus]
GTGACCTACAAGGTCGCGGTCACCCGCCGGGCGAGCCGGGACGCCGCCCGCCTGGACGCGCGGCTCAGAGAACAAAACCC
GCGCGCGGCCGACAGGCTGAGCGACCAGATCGCCCAGGCGGCCACAAGCTTGGAAGAGAGCCCTCTTCGCGGCCGCGCCG
TCGGCGCAACTACCCGCGAGATCAACATCCCCTTCGGTCGCAGCGCCTACATCGTCCGCTATCGCGTCAGAGGCCAGCAC
GTGACCATCACCCGGATCTGGCACGGCCTGGAGCAGCGCTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9334.27 Da        Isoelectric Point: 3.9962

>AT93316 WP_101715778.1 NZ_CP026100:c2336798-2336541 [Caulobacter flavus]
MADGFDIHIDPEQAARLRAAAERLGVSPSEYARELIEAGLDDLPPRTIDPDPAIDEAIADAVEAGEEETISLEEFRAQLR
SFGRR

Download         Length: 258 bp

>AT93316 NZ_CP026100:c2336798-2336541 [Caulobacter flavus]
ATGGCCGACGGCTTCGACATTCATATTGATCCTGAGCAGGCCGCCCGATTGAGGGCGGCCGCCGAGCGGCTAGGCGTTTC
GCCTTCCGAGTATGCGAGGGAACTGATCGAGGCCGGGCTAGACGACCTGCCGCCCAGGACGATCGATCCCGATCCCGCCA
TCGACGAGGCGATCGCCGACGCCGTCGAGGCCGGCGAGGAAGAAACCATCTCCCTAGAGGAGTTTCGCGCCCAGCTTCGC
AGCTTCGGCCGTCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References