Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2328400..2328634 | Replicon | chromosome |
| Accession | NZ_CP026098 | ||
| Organism | Shigella flexneri strain FDAARGOS_74 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2328530..2328633 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2328400..2328634 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MC63_RS11780 | 2324955..2325617 | - | 663 | WP_000944269.1 | exodeoxyribonuclease X | - |
| MC63_RS11785 | 2325641..2326297 | - | 657 | WP_000011667.1 | carbon-nitrogen hydrolase family protein YobB | - |
| MC63_RS11790 | 2326399..2326629 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| MC63_RS11795 | 2326768..2327142 | + | 375 | WP_025758141.1 | CopC domain-containing protein YobA | - |
| MC63_RS11800 | 2327146..2328018 | + | 873 | Protein_2244 | copper homeostasis membrane protein CopD | - |
| MC63_RS11805 | 2328031..2328372 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2328400..2328634 | - | 235 | - | - | Antitoxin |
| - | 2328530..2328633 | + | 104 | - | - | Toxin |
| MC63_RS11810 | 2328765..2329841 | - | 1077 | WP_025758140.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| MC63_RS11815 | 2329807..2330088 | - | 282 | WP_005127484.1 | excisionase | - |
| MC63_RS11820 | 2330205..2331354 | - | 1150 | Protein_2248 | IS3 family transposase | - |
| MC63_RS25220 | 2331424..2331804 | + | 381 | Protein_2249 | IS66-like element accessory protein TnpA | - |
| MC63_RS25225 | 2331806..2331973 | + | 168 | Protein_2250 | phage tail protein | - |
| MC63_RS11830 | 2331924..2332547 | + | 624 | WP_047562845.1 | DUF4376 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T93294 NZ_CP026098:2328530-2328633 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT93294 NZ_CP026098:c2328634-2328400 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
