Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pemIK/MazF(toxin) |
Location | 321767..322409 | Replicon | chromosome |
Accession | NZ_CP026095 | ||
Organism | Peribacillus asahii strain OM18 |
Toxin (Protein)
Gene name | pemK | Uniprot ID | - |
Locus tag | BAOM_RS01710 | Protein ID | WP_119118987.1 |
Coordinates | 322059..322409 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | pemI | Uniprot ID | - |
Locus tag | BAOM_RS01705 | Protein ID | WP_119118988.1 |
Coordinates | 321767..322051 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BAOM_RS01685 | 317834..318415 | - | 582 | WP_127758801.1 | rhomboid family intramembrane serine protease | - |
BAOM_RS01690 | 318493..318855 | + | 363 | WP_127758802.1 | holo-ACP synthase | - |
BAOM_RS01695 | 319167..320177 | + | 1011 | WP_127758803.1 | outer membrane lipoprotein carrier protein LolA | - |
BAOM_RS01700 | 320456..321610 | + | 1155 | WP_127762404.1 | alanine racemase | - |
BAOM_RS01705 | 321767..322051 | + | 285 | WP_119118988.1 | antitoxin endoai | Antitoxin |
BAOM_RS01710 | 322059..322409 | + | 351 | WP_119118987.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
BAOM_RS01715 | 322763..324931 | + | 2169 | WP_127762405.1 | RNA-binding transcriptional accessory protein | - |
BAOM_RS01720 | 324982..325101 | - | 120 | WP_119118989.1 | cortex morphogenetic protein CmpA | - |
BAOM_RS01725 | 325191..325652 | + | 462 | WP_127758804.1 | SprT family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 13000.10 Da Isoelectric Point: 8.4631
>T93284 WP_119118987.1 NZ_CP026095:322059-322409 [Peribacillus asahii]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITYLDETMMQKVNEALQISLGLKEF
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITYLDETMMQKVNEALQISLGLKEF
Download Length: 351 bp
>T93284 NZ_CP026095:322059-322409 [Peribacillus asahii]
ATTGTTGTTAAGCGTGGTGACGTATACTTCGCAGATCTTTCTCCAGTTGTCGGCTCAGAACAAGGTGGAACCCGTCCGGT
ACTCATTCTTCAAAATGATATCGGAAATCGCTTTAGTCCGACAGTGATTGTGGCAGCCATTACAGCTCAAATTCAAAAAG
CAAAATTGCCAACACATGTGGAGATTAATGCGAAAAAATATGGATTCGAGCGAGATTCCGTTATTCTTTTAGAACAAATT
CGCACGATTGATAAGCAACGCTTGACAGACAAAATTACGTATCTCGATGAAACAATGATGCAAAAAGTAAACGAAGCTTT
ACAGATTAGTTTAGGTTTGAAAGAATTTTAG
ATTGTTGTTAAGCGTGGTGACGTATACTTCGCAGATCTTTCTCCAGTTGTCGGCTCAGAACAAGGTGGAACCCGTCCGGT
ACTCATTCTTCAAAATGATATCGGAAATCGCTTTAGTCCGACAGTGATTGTGGCAGCCATTACAGCTCAAATTCAAAAAG
CAAAATTGCCAACACATGTGGAGATTAATGCGAAAAAATATGGATTCGAGCGAGATTCCGTTATTCTTTTAGAACAAATT
CGCACGATTGATAAGCAACGCTTGACAGACAAAATTACGTATCTCGATGAAACAATGATGCAAAAAGTAAACGAAGCTTT
ACAGATTAGTTTAGGTTTGAAAGAATTTTAG
Antitoxin
Download Length: 95 a.a. Molecular weight: 10740.05 Da Isoelectric Point: 4.7348
>AT93284 WP_119118988.1 NZ_CP026095:321767-322051 [Peribacillus asahii]
VSESGATREIIIRLPQNVLTELDGYASEENVNRSEFIYRATTMYLRKKKEFRESMKRGYIEMAAINLTIASEAFQAEYPE
YEAEHAVERLASGG
VSESGATREIIIRLPQNVLTELDGYASEENVNRSEFIYRATTMYLRKKKEFRESMKRGYIEMAAINLTIASEAFQAEYPE
YEAEHAVERLASGG
Download Length: 285 bp
>AT93284 NZ_CP026095:321767-322051 [Peribacillus asahii]
GTGTCTGAATCCGGCGCAACAAGAGAGATAATAATTCGATTACCTCAAAATGTATTAACTGAGTTAGACGGGTATGCGAG
TGAAGAAAACGTTAATCGCAGTGAGTTTATTTATCGTGCCACGACTATGTATCTTCGTAAAAAGAAAGAATTTCGGGAAT
CAATGAAACGTGGCTATATTGAAATGGCGGCCATTAATTTAACAATCGCTTCTGAAGCATTTCAGGCTGAATATCCAGAA
TATGAAGCTGAACATGCTGTCGAGCGATTAGCTAGTGGAGGCTGA
GTGTCTGAATCCGGCGCAACAAGAGAGATAATAATTCGATTACCTCAAAATGTATTAACTGAGTTAGACGGGTATGCGAG
TGAAGAAAACGTTAATCGCAGTGAGTTTATTTATCGTGCCACGACTATGTATCTTCGTAAAAAGAAAGAATTTCGGGAAT
CAATGAAACGTGGCTATATTGAAATGGCGGCCATTAATTTAACAATCGCTTCTGAAGCATTTCAGGCTGAATATCCAGAA
TATGAAGCTGAACATGCTGTCGAGCGATTAGCTAGTGGAGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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