Detailed information of TA system TA093284

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pemIK/MazF(toxin)
• Location: 321767..322409
• Replicon: chromosome
• Accession: NZ_CP026095
• Organism: Peribacillus asahii strain OM18

Toxin (Protein)

• Gene name: pemK
• Uniprot ID: -
• Locus tag: BAOM_RS01710
• Protein ID: WP_119118987.1
• Coordinates: 322059..322409 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: pemI
• Uniprot ID: -
• Locus tag: BAOM_RS01705
• Protein ID: WP_119118988.1
• Coordinates: 321767..322051 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BAOM_RS01685	317834..318415	-	582	WP_127758801.1	rhomboid family intramembrane serine protease	-
BAOM_RS01690	318493..318855	+	363	WP_127758802.1	holo-ACP synthase	-
BAOM_RS01695	319167..320177	+	1011	WP_127758803.1	outer membrane lipoprotein carrier protein LolA	-
BAOM_RS01700	320456..321610	+	1155	WP_127762404.1	alanine racemase	-
BAOM_RS01705	321767..322051	+	285	WP_119118988.1	antitoxin endoai	Antitoxin
BAOM_RS01710	322059..322409	+	351	WP_119118987.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
BAOM_RS01715	322763..324931	+	2169	WP_127762405.1	RNA-binding transcriptional accessory protein	-
BAOM_RS01720	324982..325101	-	120	WP_119118989.1	cortex morphogenetic protein CmpA	-
BAOM_RS01725	325191..325652	+	462	WP_127758804.1	SprT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (1-113)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13000.10 Da
• Isoelectric Point: 8.4631

>T93284 WP_119118987.1 NZ_CP026095:322059-322409 [Peribacillus asahii]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITYLDETMMQKVNEALQISLGLKEF

Nucleotide

• Length: 351 bp

>T93284 NZ_CP026095:322059-322409 [Peribacillus asahii]
ATTGTTGTTAAGCGTGGTGACGTATACTTCGCAGATCTTTCTCCAGTTGTCGGCTCAGAACAAGGTGGAACCCGTCCGGT
ACTCATTCTTCAAAATGATATCGGAAATCGCTTTAGTCCGACAGTGATTGTGGCAGCCATTACAGCTCAAATTCAAAAAG
CAAAATTGCCAACACATGTGGAGATTAATGCGAAAAAATATGGATTCGAGCGAGATTCCGTTATTCTTTTAGAACAAATT
CGCACGATTGATAAGCAACGCTTGACAGACAAAATTACGTATCTCGATGAAACAATGATGCAAAAAGTAAACGAAGCTTT
ACAGATTAGTTTAGGTTTGAAAGAATTTTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10740.05 Da
• Isoelectric Point: 4.7348

>AT93284 WP_119118988.1 NZ_CP026095:321767-322051 [Peribacillus asahii]
VSESGATREIIIRLPQNVLTELDGYASEENVNRSEFIYRATTMYLRKKKEFRESMKRGYIEMAAINLTIASEAFQAEYPE
YEAEHAVERLASGG

Nucleotide

• Length: 285 bp

>AT93284 NZ_CP026095:321767-322051 [Peribacillus asahii]
GTGTCTGAATCCGGCGCAACAAGAGAGATAATAATTCGATTACCTCAAAATGTATTAACTGAGTTAGACGGGTATGCGAG
TGAAGAAAACGTTAATCGCAGTGAGTTTATTTATCGTGCCACGACTATGTATCTTCGTAAAAAGAAAGAATTTCGGGAAT
CAATGAAACGTGGCTATATTGAAATGGCGGCCATTAATTTAACAATCGCTTCTGAAGCATTTCAGGCTGAATATCCAGAA
TATGAAGCTGAACATGCTGTCGAGCGATTAGCTAGTGGAGGCTGA