Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2026214..2026485 Replicon chromosome
Accession NZ_CP026085
Organism Escherichia coli strain DH5alpha

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2026344..2026447 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2026214..2026485 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1467_RS10480 2022769..2023431 - 663 WP_000944256.1 exodeoxyribonuclease X -
C1467_RS10485 2023455..2024111 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C1467_RS10490 2024213..2024443 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C1467_RS10495 2024582..2024956 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C1467_RS10500 2024960..2025832 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
C1467_RS10505 2025845..2026186 + 342 WP_000976472.1 YebY family protein -
- 2026214..2026485 - 272 - - Antitoxin
- 2026344..2026447 + 104 - - Toxin
C1467_RS10510 2026582..2027238 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
C1467_RS10515 2027239..2027430 - 192 WP_001296140.1 YebW family protein -
C1467_RS10520 2027535..2027771 - 237 WP_001295499.1 DUF1480 family protein -
C1467_RS10525 2027889..2029328 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T93255 NZ_CP026085:2026344-2026447 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT93255 NZ_CP026085:c2026485-2026214 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References