Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 2815643..2816055 Replicon chromosome
Accession NZ_CP026050
Organism Serratia marcescens strain FDAARGOS_65

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MC51_RS13285 Protein ID WP_052133471.1
Coordinates 2815643..2815858 (-) Length 72 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MC51_RS13290 Protein ID WP_033649649.1
Coordinates 2815858..2816055 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MC51_RS13275 2811060..2812523 - 1464 WP_047569797.1 serralysin family metalloprotease -
MC51_RS13280 2813205..2815523 + 2319 WP_047569799.1 zinc/cadmium/mercury/lead-transporting ATPase -
MC51_RS13285 2815643..2815858 - 216 WP_052133471.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MC51_RS13290 2815858..2816055 - 198 WP_033649649.1 hypothetical protein Antitoxin
MC51_RS13295 2816117..2816362 - 246 WP_025304890.1 sulfurtransferase TusA -
MC51_RS13300 2816583..2817242 + 660 WP_033636672.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
MC51_RS13305 2817284..2817718 + 435 WP_047569800.1 GNAT family N-acetyltransferase -
MC51_RS13310 2817799..2818362 + 564 WP_033636670.1 DcrB family lipoprotein -
MC51_RS13315 2818398..2819597 - 1200 WP_033654019.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
MC51_RS13320 2819594..2820862 - 1269 WP_047569803.1 glycerol-3-phosphate dehydrogenase subunit GlpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-71)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8183.65 Da        Isoelectric Point: 10.4174

>T92948 WP_052133471.1 NZ_CP026050:c2815858-2815643 [Serratia marcescens]
MLNIEWTRAARQDLAEIVGFIANDNPLAARKMKVLIMEAVIPAARHPRIFRRGRVDGTHEIPLHPHYLLVY

Download         Length: 216 bp

>T92948 NZ_CP026050:c2815858-2815643 [Serratia marcescens]
ATGCTCAACATCGAATGGACTCGAGCCGCACGTCAGGATCTGGCGGAGATTGTGGGATTCATCGCCAATGATAACCCTCT
GGCGGCCAGAAAAATGAAGGTTCTCATCATGGAGGCCGTCATTCCCGCCGCCAGACATCCTCGAATTTTCCGGCGCGGCA
GAGTGGACGGCACGCATGAAATCCCCCTACATCCCCATTATCTCCTGGTTTACTAG

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT92948 WP_033649649.1 NZ_CP026050:c2816055-2815858 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp

>AT92948 NZ_CP026050:c2816055-2815858 [Serratia marcescens]
ATGAGTATTTTACTACTGCCTACGGTTGCCAAGATGGAAAATGAGGAACGTACACAGGGCTATGAGCGCTGGTTTCTTGA
AAGAGTTCAGGAAGCCATGGATGAGCCGCGGCCCGGCATTCCTCATGATGACGTGATGGCTGAAATGGATGCTGTTATCG
CTGCTGCAGAAGCCAGGATCAAAGCGAAGCAGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References