Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1998718..1998863 | Replicon | chromosome |
| Accession | NZ_CP026021 | ||
| Organism | Klebsiella pneumoniae strain 11492 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1998754..1998856 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1998718..1998863 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C2D60_RS09840 | 1993848..1995908 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| C2D60_RS09845 | 1995912..1996571 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| C2D60_RS09850 | 1996650..1996880 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| C2D60_RS09855 | 1996993..1997367 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| C2D60_RS09860 | 1997371..1998240 | + | 870 | WP_014907333.1 | copper homeostasis membrane protein CopD | - |
| C2D60_RS09865 | 1998257..1998595 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1998718..1998863 | - | 146 | - | - | Antitoxin |
| - | 1998754..1998856 | + | 103 | - | - | Toxin |
| C2D60_RS27230 | 1999231..1999374 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| C2D60_RS09875 | 1999479..2000447 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| C2D60_RS09880 | 2000604..2001257 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| C2D60_RS09885 | 2001254..2001445 | - | 192 | WP_002911395.1 | YebW family protein | - |
| C2D60_RS09890 | 2001543..2001782 | - | 240 | WP_002911393.1 | YebV family protein | - |
| C2D60_RS09895 | 2001898..2003331 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T92718 NZ_CP026021:1998754-1998856 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT92718 NZ_CP026021:c1998863-1998718 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT