Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1989888..1990032 Replicon chromosome
Accession NZ_CP026013
Organism Klebsiella variicola strain 13450

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1989924..1990026 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1989888..1990032 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2D62_RS09580 1985744..1986403 - 660 WP_022066251.1 exodeoxyribonuclease X -
C2D62_RS09585 1986482..1986712 - 231 WP_012541260.1 DNA polymerase III subunit theta -
C2D62_RS09590 1986826..1987200 + 375 WP_008804269.1 CopC domain-containing protein YobA -
C2D62_RS09595 1987204..1988073 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
C2D62_RS09600 1988090..1988464 + 375 WP_181646003.1 YebY family protein -
C2D62_RS09605 1988534..1989742 + 1209 WP_001352368.1 IS4-like element ISVsa5 family transposase -
- 1989888..1990032 - 145 - - Antitoxin
- 1989924..1990026 + 103 - - Toxin
C2D62_RS09610 1990411..1990554 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
C2D62_RS09615 1990658..1991647 - 990 WP_032691211.1 VirK/YbjX family protein -
C2D62_RS09620 1991783..1992436 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
C2D62_RS09625 1992433..1992624 - 192 WP_002911395.1 YebW family protein -
C2D62_RS09630 1992722..1992961 - 240 WP_002911393.1 YebV family protein -
C2D62_RS09635 1993077..1994510 - 1434 WP_012967754.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1988534..1989742 1208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T92678 NZ_CP026013:1989924-1990026 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT92678 NZ_CP026013:c1990032-1989888 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References