Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1909540..1909685 Replicon chromosome
Accession NZ_CP026011
Organism Klebsiella pneumoniae strain K2044

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1909576..1909678 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1909540..1909685 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2D63_RS09055 1904670..1906730 + 2061 WP_004151449.1 oligopeptidase B -
C2D63_RS09060 1906734..1907393 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2D63_RS09065 1907472..1907702 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2D63_RS09070 1907815..1908189 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2D63_RS09075 1908193..1909062 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
C2D63_RS09080 1909079..1909417 + 339 WP_002911404.1 YebY family protein -
- 1909540..1909685 - 146 - - Antitoxin
- 1909576..1909678 + 103 - - Toxin
C2D63_RS09085 1910053..1910196 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2D63_RS09090 1910301..1911269 - 969 WP_014907334.1 VirK/YbjX family protein -
C2D63_RS09095 1911426..1912079 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C2D63_RS09100 1912076..1912267 - 192 WP_002911395.1 YebW family protein -
C2D63_RS09105 1912365..1912604 - 240 WP_002911393.1 YebV family protein -
C2D63_RS09110 1912720..1914153 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T92657 NZ_CP026011:1909576-1909678 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT92657 NZ_CP026011:c1909685-1909540 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References