Detailed information of TA system TA092640

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 2680324..2680869
• Replicon: chromosome
• Accession: NZ_CP025987
• Organism: Marinomonas sp. FW-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: C1X04_RS12450
• Protein ID: WP_137170102.1
• Coordinates: 2680603..2680869 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: C1X04_RS12445
• Protein ID: WP_137170101.1
• Coordinates: 2680324..2680566 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1X04_RS12415	2675985..2676974	+	990	WP_137170097.1	2-dehydropantoate 2-reductase	-
C1X04_RS12425	2677453..2677899	-	447	WP_137170099.1	DUF1499 domain-containing protein	-
C1X04_RS12430	2677927..2678271	-	345	WP_110573760.1	helix-turn-helix transcriptional regulator	-
C1X04_RS12435	2678382..2679149	+	768	WP_110573762.1	SDR family oxidoreductase	-
C1X04_RS12440	2679196..2679516	+	321	WP_137170100.1	YdhR family protein	-
C1X04_RS12445	2680324..2680566	+	243	WP_137170101.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C1X04_RS12450	2680603..2680869	+	267	WP_137170102.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C1X04_RS12455	2680936..2681871	+	936	WP_137170103.1	AraC family transcriptional regulator	-
C1X04_RS12460	2681868..2683091	-	1224	WP_137170104.1	MFS transporter	-
C1X04_RS12465	2683233..2683553	-	321	WP_137170105.1	hypothetical protein	-
C1X04_RS12470	2683614..2684300	-	687	WP_137170106.1	YafY family transcriptional regulator	-
C1X04_RS12475	2684415..2685536	+	1122	WP_137170107.1	FAD-dependent monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-56)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10159.51 Da
• Isoelectric Point: 9.4441

>T92640 WP_137170102.1 NZ_CP025987:2680603-2680869 [Marinomonas sp. FW-1]
MAQTHLQKIKSYTVHNFSEAQRQNYKHTLLTGFQMLADNPDLSRRCDEVYPNGFYFPVGKHSAYFTKEGGFILVVTVLAQ
SQRPQNHL

Nucleotide

• Length: 267 bp

>T92640 NZ_CP025987:2680603-2680869 [Marinomonas sp. FW-1]
TTGGCTCAGACTCATTTACAAAAAATCAAAAGCTATACCGTCCACAATTTTTCTGAAGCACAGAGGCAAAACTATAAACA
CACATTATTGACTGGGTTTCAAATGCTAGCCGACAATCCAGACTTAAGCCGTCGTTGCGATGAAGTTTATCCAAATGGTT
TTTACTTTCCAGTTGGCAAACACTCGGCTTACTTTACAAAAGAAGGCGGTTTTATTTTGGTAGTGACTGTACTCGCTCAA
TCACAACGCCCACAGAACCACTTGTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9079.30 Da
• Isoelectric Point: 4.7961

>AT92640 WP_137170101.1 NZ_CP025987:2680324-2680566 [Marinomonas sp. FW-1]
MRTLTANDTKRNFGELLLSAQREPVKISKNSKDAVVVMSIRDYEELEAMKTDYLKHCFESAKQDLVQGNVVDGEDFLNAL

Nucleotide

• Length: 243 bp

>AT92640 NZ_CP025987:2680324-2680566 [Marinomonas sp. FW-1]
ATGCGAACATTAACAGCAAATGATACCAAGCGTAACTTTGGTGAACTTCTGCTAAGCGCCCAACGTGAGCCAGTTAAAAT
TAGCAAAAACAGCAAAGATGCCGTTGTGGTAATGTCTATCAGAGACTATGAAGAACTAGAAGCAATGAAAACGGACTACC
TTAAACATTGTTTCGAGTCAGCTAAACAAGACTTGGTACAAGGCAATGTGGTTGATGGCGAAGATTTCCTAAACGCCTTG
TAA