Detailed information of TA system TA092638

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1522184..1522712
• Replicon: chromosome
• Accession: NZ_CP025987
• Organism: Marinomonas sp. FW-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C1X04_RS07105
• Protein ID: WP_137169528.1
• Coordinates: 1522184..1522471 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C1X04_RS07110
• Protein ID: WP_137169529.1
• Coordinates: 1522461..1522712 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1X04_RS07080	1517788..1518774	-	987	WP_137169525.1	isopenicillin N synthase family oxygenase	-
C1X04_RS07085	1518927..1519403	-	477	WP_137169526.1	nucleoside deaminase	-
C1X04_RS07090	1519407..1520198	-	792	WP_110571834.1	ABC transporter permease	-
C1X04_RS07095	1520176..1520964	-	789	WP_137170741.1	ABC transporter ATP-binding protein	-
C1X04_RS07100	1520984..1521979	-	996	WP_137169527.1	ABC transporter substrate-binding protein	-
C1X04_RS07105	1522184..1522471	-	288	WP_137169528.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C1X04_RS07110	1522461..1522712	-	252	WP_137169529.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
C1X04_RS07115	1522812..1523114	-	303	WP_137169530.1	cupin domain-containing protein	-
C1X04_RS07120	1523316..1524815	+	1500	WP_137169531.1	xanthine dehydrogenase small subunit	-
C1X04_RS07125	1524808..1527156	+	2349	WP_137169532.1	xanthine dehydrogenase molybdopterin binding subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11048.03 Da
• Isoelectric Point: 10.4579

>T92638 WP_137169528.1 NZ_CP025987:c1522471-1522184 [Marinomonas sp. FW-1]
MTYKLKFLPAALKEWRKLAPQIQTQFKKKLAERLDNPHVPASKLRGYDYVYKIKLRTSGYRLAYEVIDDEVVVYVLAIGK
RDKDAVYKKLASRAG

Nucleotide

• Length: 288 bp

>T92638 NZ_CP025987:c1522471-1522184 [Marinomonas sp. FW-1]
ATGACTTATAAATTAAAATTTCTTCCTGCAGCTCTAAAAGAATGGCGCAAATTAGCACCACAAATCCAAACACAATTTAA
AAAGAAGTTAGCAGAGCGACTAGACAACCCGCATGTTCCAGCCTCAAAACTACGTGGTTATGATTACGTCTACAAAATAA
AACTAAGAACCTCAGGCTACCGCCTAGCTTATGAAGTCATAGACGATGAAGTCGTCGTTTATGTGCTGGCAATTGGAAAA
CGAGACAAAGACGCGGTTTATAAAAAACTCGCTTCTCGGGCTGGTTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9143.49 Da
• Isoelectric Point: 4.2950

>AT92638 WP_137169529.1 NZ_CP025987:c1522712-1522461 [Marinomonas sp. FW-1]
MRQILANYTASISELKKNPTALLNESDGSAIAILNHNKPAAYLVPAEAYELLMEMVDDIELAKLVEARRTDLSKAIEVSL
DDL

Nucleotide

• Length: 252 bp

>AT92638 NZ_CP025987:c1522712-1522461 [Marinomonas sp. FW-1]
ATGAGACAAATCTTAGCCAATTACACAGCCAGTATTTCTGAATTAAAGAAAAACCCAACGGCTTTACTTAACGAATCTGA
TGGCTCTGCTATAGCCATTTTAAACCACAATAAGCCAGCGGCTTACCTCGTCCCTGCTGAGGCCTATGAGCTTTTGATGG
AGATGGTCGATGATATTGAACTAGCAAAACTAGTTGAGGCTCGCCGTACTGATTTATCCAAAGCCATCGAAGTGAGTTTA
GATGACTTATAA