Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1488323..1488852 Replicon chromosome
Accession NZ_CP025987
Organism Marinomonas sp. FW-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C1X04_RS06950 Protein ID WP_137169512.1
Coordinates 1488562..1488852 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag C1X04_RS06945 Protein ID WP_110571807.1
Coordinates 1488323..1488565 (+) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1X04_RS06925 1483648..1484712 - 1065 WP_110571804.1 FAD:protein FMN transferase -
C1X04_RS06930 1484828..1485814 - 987 WP_110572805.1 AraC family transcriptional regulator -
C1X04_RS06935 1485939..1487144 + 1206 WP_110571805.1 MFS transporter -
C1X04_RS06940 1487345..1488151 - 807 WP_110571806.1 M48 family metallopeptidase -
C1X04_RS06945 1488323..1488565 + 243 WP_110571807.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
C1X04_RS06950 1488562..1488852 + 291 WP_137169512.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C1X04_RS06955 1489048..1489743 + 696 WP_110571809.1 MFS transporter -
C1X04_RS06960 1490023..1491000 + 978 WP_110571810.1 dipeptidase -
C1X04_RS06965 1491065..1491610 + 546 WP_137169513.1 hydrocarbon binding protein -
C1X04_RS06970 1491709..1493775 + 2067 WP_110571812.1 dimethylglycine demethylation protein DgcA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-91)

Antitoxin

(1-76)


Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11153.81 Da        Isoelectric Point: 9.7946

>T92637 WP_137169512.1 NZ_CP025987:1488562-1488852 [Marinomonas sp. FW-1]
MNLFTLSNAARADIKKIATYTQKVWGSDKRRTYIKELDATMLFLADNPISGTQCDYIASGLRKHQHQSHTIFYEIQRDSI
FIVRVLHKSMDVESKF

Download         Length: 291 bp

>T92637 NZ_CP025987:1488562-1488852 [Marinomonas sp. FW-1]
ATGAATTTGTTTACTTTGTCGAACGCGGCACGTGCCGACATTAAGAAAATAGCTACCTATACACAGAAAGTATGGGGTTC
AGACAAGCGTAGAACTTACATCAAAGAATTAGATGCAACGATGCTTTTTTTAGCAGATAACCCTATATCAGGTACGCAAT
GTGACTATATAGCTTCAGGCTTACGGAAACACCAACATCAAAGCCATACTATATTTTATGAAATTCAAAGGGACTCAATC
TTTATTGTTCGGGTACTTCATAAAAGCATGGATGTCGAGTCGAAGTTTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8777.79 Da        Isoelectric Point: 4.4217

>AT92637 WP_110571807.1 NZ_CP025987:1488323-1488565 [Marinomonas sp. FW-1]
MPKNTSISLGSHFDQFIAQQIADGRYASASEVIRAGLRKLEDDDQKLKALQSLIQEGVASGTAEYSYEGLMKELDDELGK

Download         Length: 243 bp

>AT92637 NZ_CP025987:1488323-1488565 [Marinomonas sp. FW-1]
ATGCCTAAAAATACAAGCATTAGTTTAGGTAGTCATTTTGATCAGTTTATTGCACAGCAAATAGCAGATGGGCGATACGC
CTCCGCTAGTGAAGTCATCCGTGCTGGATTGCGTAAACTTGAAGATGATGATCAAAAACTTAAAGCACTGCAAAGCTTAA
TACAAGAAGGTGTTGCTAGTGGCACTGCCGAATACAGCTATGAAGGCTTGATGAAAGAGCTTGATGACGAATTGGGTAAA
TGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References