Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/ParE-RHH |
Location | 1488323..1488852 | Replicon | chromosome |
Accession | NZ_CP025987 | ||
Organism | Marinomonas sp. FW-1 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | C1X04_RS06950 | Protein ID | WP_137169512.1 |
Coordinates | 1488562..1488852 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | C1X04_RS06945 | Protein ID | WP_110571807.1 |
Coordinates | 1488323..1488565 (+) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C1X04_RS06925 | 1483648..1484712 | - | 1065 | WP_110571804.1 | FAD:protein FMN transferase | - |
C1X04_RS06930 | 1484828..1485814 | - | 987 | WP_110572805.1 | AraC family transcriptional regulator | - |
C1X04_RS06935 | 1485939..1487144 | + | 1206 | WP_110571805.1 | MFS transporter | - |
C1X04_RS06940 | 1487345..1488151 | - | 807 | WP_110571806.1 | M48 family metallopeptidase | - |
C1X04_RS06945 | 1488323..1488565 | + | 243 | WP_110571807.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
C1X04_RS06950 | 1488562..1488852 | + | 291 | WP_137169512.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C1X04_RS06955 | 1489048..1489743 | + | 696 | WP_110571809.1 | MFS transporter | - |
C1X04_RS06960 | 1490023..1491000 | + | 978 | WP_110571810.1 | dipeptidase | - |
C1X04_RS06965 | 1491065..1491610 | + | 546 | WP_137169513.1 | hydrocarbon binding protein | - |
C1X04_RS06970 | 1491709..1493775 | + | 2067 | WP_110571812.1 | dimethylglycine demethylation protein DgcA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11153.81 Da Isoelectric Point: 9.7946
>T92637 WP_137169512.1 NZ_CP025987:1488562-1488852 [Marinomonas sp. FW-1]
MNLFTLSNAARADIKKIATYTQKVWGSDKRRTYIKELDATMLFLADNPISGTQCDYIASGLRKHQHQSHTIFYEIQRDSI
FIVRVLHKSMDVESKF
MNLFTLSNAARADIKKIATYTQKVWGSDKRRTYIKELDATMLFLADNPISGTQCDYIASGLRKHQHQSHTIFYEIQRDSI
FIVRVLHKSMDVESKF
Download Length: 291 bp
>T92637 NZ_CP025987:1488562-1488852 [Marinomonas sp. FW-1]
ATGAATTTGTTTACTTTGTCGAACGCGGCACGTGCCGACATTAAGAAAATAGCTACCTATACACAGAAAGTATGGGGTTC
AGACAAGCGTAGAACTTACATCAAAGAATTAGATGCAACGATGCTTTTTTTAGCAGATAACCCTATATCAGGTACGCAAT
GTGACTATATAGCTTCAGGCTTACGGAAACACCAACATCAAAGCCATACTATATTTTATGAAATTCAAAGGGACTCAATC
TTTATTGTTCGGGTACTTCATAAAAGCATGGATGTCGAGTCGAAGTTTTGA
ATGAATTTGTTTACTTTGTCGAACGCGGCACGTGCCGACATTAAGAAAATAGCTACCTATACACAGAAAGTATGGGGTTC
AGACAAGCGTAGAACTTACATCAAAGAATTAGATGCAACGATGCTTTTTTTAGCAGATAACCCTATATCAGGTACGCAAT
GTGACTATATAGCTTCAGGCTTACGGAAACACCAACATCAAAGCCATACTATATTTTATGAAATTCAAAGGGACTCAATC
TTTATTGTTCGGGTACTTCATAAAAGCATGGATGTCGAGTCGAAGTTTTGA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8777.79 Da Isoelectric Point: 4.4217
>AT92637 WP_110571807.1 NZ_CP025987:1488323-1488565 [Marinomonas sp. FW-1]
MPKNTSISLGSHFDQFIAQQIADGRYASASEVIRAGLRKLEDDDQKLKALQSLIQEGVASGTAEYSYEGLMKELDDELGK
MPKNTSISLGSHFDQFIAQQIADGRYASASEVIRAGLRKLEDDDQKLKALQSLIQEGVASGTAEYSYEGLMKELDDELGK
Download Length: 243 bp
>AT92637 NZ_CP025987:1488323-1488565 [Marinomonas sp. FW-1]
ATGCCTAAAAATACAAGCATTAGTTTAGGTAGTCATTTTGATCAGTTTATTGCACAGCAAATAGCAGATGGGCGATACGC
CTCCGCTAGTGAAGTCATCCGTGCTGGATTGCGTAAACTTGAAGATGATGATCAAAAACTTAAAGCACTGCAAAGCTTAA
TACAAGAAGGTGTTGCTAGTGGCACTGCCGAATACAGCTATGAAGGCTTGATGAAAGAGCTTGATGACGAATTGGGTAAA
TGA
ATGCCTAAAAATACAAGCATTAGTTTAGGTAGTCATTTTGATCAGTTTATTGCACAGCAAATAGCAGATGGGCGATACGC
CTCCGCTAGTGAAGTCATCCGTGCTGGATTGCGTAAACTTGAAGATGATGATCAAAAACTTAAAGCACTGCAAAGCTTAA
TACAAGAAGGTGTTGCTAGTGGCACTGCCGAATACAGCTATGAAGGCTTGATGAAAGAGCTTGATGACGAATTGGGTAAA
TGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|