Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1179336..1179568 Replicon chromosome
Accession NZ_CP025979
Organism Escherichia marmotae strain HT073016

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1179337..1179440 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1179336..1179568 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1192_RS06255 1175469..1175807 + 339 WP_000149055.1 DUF1971 domain-containing protein -
C1192_RS06265 1176397..1177134 - 738 WP_052463016.1 hypothetical protein -
C1192_RS06275 1178405..1179205 + 801 WP_077784531.1 tyrosine-type recombinase/integrase -
- 1179336..1179568 + 233 - - Antitoxin
- 1179337..1179440 - 104 - - Toxin
C1192_RS06280 1179598..1179939 - 342 WP_000976465.1 YebY family protein -
C1192_RS06285 1179952..1180824 - 873 WP_038354771.1 copper homeostasis membrane protein CopD -
C1192_RS06290 1180828..1181202 - 375 WP_000168753.1 CopC domain-containing protein YobA -
C1192_RS06295 1181341..1181571 + 231 WP_000916764.1 DNA polymerase III subunit theta -
C1192_RS06300 1181672..1182328 + 657 WP_000122137.1 carbon-nitrogen hydrolase family protein -
C1192_RS06305 1182353..1183015 + 663 WP_000944296.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1172023..1183015 10992


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T92612 NZ_CP025979:c1179440-1179337 [Escherichia marmotae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 233 bp

>AT92612 NZ_CP025979:1179336-1179568 [Escherichia marmotae]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCCGCGCGTAAAGTGGTCAGA
AAAAAAGCGCGTTTATCATCCTCTAAAATGTTAAAAACCGCCCGTTCTGGTGAAAGCACCCGAGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References