Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1906574..1906719 Replicon chromosome
Accession NZ_CP025963
Organism Klebsiella pneumoniae strain WCHKP020034

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1906610..1906712 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1906574..1906719 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEA73_RS09510 1901704..1903764 + 2061 WP_004151449.1 oligopeptidase B -
CEA73_RS09515 1903768..1904427 - 660 WP_002911407.1 exodeoxyribonuclease X -
CEA73_RS09520 1904506..1904736 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CEA73_RS09525 1904849..1905223 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CEA73_RS09530 1905227..1906096 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CEA73_RS09535 1906113..1906451 + 339 WP_004189269.1 YebY family protein -
- 1906574..1906719 - 146 - - Antitoxin
- 1906610..1906712 + 103 - - Toxin
CEA73_RS29535 1907086..1907229 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CEA73_RS09545 1907334..1908302 - 969 WP_004151446.1 VirK/YbjX family protein -
CEA73_RS09550 1908459..1909112 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
CEA73_RS09555 1909109..1909300 - 192 WP_002911395.1 YebW family protein -
CEA73_RS09560 1909398..1909637 - 240 WP_002911393.1 YebV family protein -
CEA73_RS09565 1909753..1911186 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T92593 NZ_CP025963:1906610-1906712 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT92593 NZ_CP025963:c1906719-1906574 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References