Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3635639..3636220 Replicon chromosome
Accession NZ_CP025938
Organism Tamlana carrageenivorans strain UJ94

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C1A40_RS16015 Protein ID WP_102996779.1
Coordinates 3635639..3635938 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C1A40_RS16020 Protein ID WP_102996780.1
Coordinates 3635942..3636220 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1A40_RS15995 3630954..3631958 - 1005 WP_102996775.1 IS30 family transposase -
C1A40_RS16000 3632737..3633519 + 783 WP_102996776.1 hypothetical protein -
C1A40_RS16005 3633683..3634420 + 738 WP_102996777.1 hypothetical protein -
C1A40_RS16010 3634430..3635407 + 978 WP_102996778.1 hypothetical protein -
C1A40_RS16015 3635639..3635938 + 300 WP_102996779.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C1A40_RS16020 3635942..3636220 + 279 WP_102996780.1 putative addiction module antidote protein Antitoxin
C1A40_RS16025 3636437..3637441 + 1005 WP_102994224.1 IS30 family transposase -
C1A40_RS16030 3637481..3638065 + 585 WP_102996781.1 hypothetical protein -
C1A40_RS16035 3638273..3639277 + 1005 WP_102994224.1 IS30 family transposase -
C1A40_RS16040 3639565..3640923 + 1359 WP_102996782.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3378229..3689745 311516


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-92)

Antitoxin

Uncharacterized protein HI1420

(9-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11760.94 Da        Isoelectric Point: 10.4596

>T92521 WP_102996779.1 NZ_CP025938:3635639-3635938 [Tamlana carrageenivorans]
MFFIEKTTEFDKWLKKLKDFKAKAKILFRIQKLETDEHFGDCKTVGDGIREMRINFAKGYRIYFKEKDGKIIVLLIGGDK
STQQKDIVKAKEIWKKLNK

Download         Length: 300 bp

>T92521 NZ_CP025938:3635639-3635938 [Tamlana carrageenivorans]
ATGTTCTTTATTGAAAAAACAACTGAATTTGACAAATGGCTAAAAAAGTTAAAAGACTTTAAGGCAAAAGCAAAGATTTT
ATTCAGAATTCAAAAATTAGAAACGGATGAACATTTTGGAGATTGTAAAACGGTAGGCGACGGAATTCGTGAAATGCGAA
TAAATTTTGCGAAAGGTTACAGAATTTACTTCAAAGAAAAAGACGGAAAAATTATTGTCCTTTTGATTGGTGGAGATAAA
TCAACTCAACAAAAGGATATTGTGAAAGCTAAAGAAATTTGGAAAAAATTAAATAAATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9842.33 Da        Isoelectric Point: 5.0351

>AT92521 WP_102996780.1 NZ_CP025938:3635942-3636220 [Tamlana carrageenivorans]
MGTSKFEIADYLDSKEMIAEYLNSVLEEGNNADIINAIGHIAKSIGMTKIAEETGLSRPSLYKALSDGAKPQFATIMKVL
KAIGGQIQVNPA

Download         Length: 279 bp

>AT92521 NZ_CP025938:3635942-3636220 [Tamlana carrageenivorans]
ATGGGAACTTCAAAATTTGAAATTGCTGATTATTTAGATAGTAAAGAAATGATTGCGGAATATCTAAATTCAGTTCTCGA
AGAAGGAAATAATGCGGATATCATTAATGCAATTGGACATATTGCAAAGTCTATCGGAATGACAAAAATTGCGGAAGAAA
CTGGTTTAAGTAGACCTAGTTTGTATAAAGCATTATCCGATGGAGCGAAACCTCAATTTGCTACAATTATGAAAGTACTA
AAAGCTATTGGAGGACAAATCCAAGTGAATCCAGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References