Detailed information of TA system TA092520

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 1117674..1118215
• Replicon: chromosome
• Accession: NZ_CP025938
• Organism: Tamlana carrageenivorans strain UJ94

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: C1A40_RS05100
• Protein ID: WP_102994953.1
• Coordinates: 1117913..1118215 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: C1A40_RS05095
• Protein ID: WP_102994952.1
• Coordinates: 1117674..1117916 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1A40_RS05080	1113741..1113989	+	249	WP_158651273.1	hypothetical protein	-
C1A40_RS05085	1113993..1114379	+	387	WP_102994950.1	(deoxy)nucleoside triphosphate pyrophosphohydrolase	-
C1A40_RS05090	1114376..1117513	+	3138	WP_102994951.1	DEAD/DEAH box helicase	-
C1A40_RS05095	1117674..1117916	+	243	WP_102994952.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
C1A40_RS05100	1117913..1118215	+	303	WP_102994953.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C1A40_RS05105	1118391..1119017	+	627	Protein_1008	transposase	-
C1A40_RS05110	1119090..1119830	-	741	WP_102994954.1	IS21-like element helper ATPase IstB	-
C1A40_RS05115	1119868..1121422	-	1555	Protein_1010	IS21 family transposase	-
C1A40_RS05120	1121629..1122894	+	1266	Protein_1011	sialate O-acetylesterase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-94)

Antitoxin

• Antitoxin ParD (1-79)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 12285.25 Da
• Isoelectric Point: 10.0134

>T92520 WP_102994953.1 NZ_CP025938:1117913-1118215 [Tamlana carrageenivorans]
MSKNKYRISKQAIDDLNDIWVYTFHKWSKEQADRYYDLIIGEIEFIADHYLIGKSAEQTRKNYRVTKIKSHLIFYRKVEH
DIVEIVRILHERMDLKKRLK

Nucleotide

• Length: 303 bp

>T92520 NZ_CP025938:1117913-1118215 [Tamlana carrageenivorans]
ATGAGTAAAAACAAATATCGAATAAGTAAACAAGCGATTGATGATTTAAATGATATTTGGGTATATACTTTTCACAAATG
GTCTAAAGAACAAGCCGACAGATATTACGACTTGATAATCGGAGAGATTGAATTTATAGCGGACCACTATTTAATTGGAA
AATCGGCTGAACAAACTCGAAAAAACTATCGCGTAACAAAAATCAAATCGCATCTGATTTTTTACAGAAAGGTTGAGCAT
GACATTGTCGAAATCGTTAGAATTTTACATGAAAGAATGGATCTTAAAAAACGACTGAAATAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9270.45 Da
• Isoelectric Point: 6.7294

>AT92520 WP_102994952.1 NZ_CP025938:1117674-1117916 [Tamlana carrageenivorans]
MGKNTSISLGNHFEDFIREEVKSGRYGSVSEVIRSALRLLEREEKKERELIKALEVGENSGFIENFDPKQNLTDLHRKHL

Nucleotide

• Length: 243 bp

>AT92520 NZ_CP025938:1117674-1117916 [Tamlana carrageenivorans]
ATGGGAAAAAACACATCAATTTCACTCGGAAATCATTTTGAGGATTTTATCAGAGAAGAAGTAAAATCAGGCAGATATGG
TTCGGTAAGCGAAGTTATCCGTTCTGCATTACGTTTGCTGGAACGTGAAGAAAAAAAGGAAAGAGAATTAATTAAAGCAC
TCGAAGTAGGTGAAAATAGTGGTTTTATTGAAAATTTTGATCCAAAACAAAACCTGACTGATTTACATCGCAAACACTTA
TGA