Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1117674..1118215 Replicon chromosome
Accession NZ_CP025938
Organism Tamlana carrageenivorans strain UJ94

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C1A40_RS05100 Protein ID WP_102994953.1
Coordinates 1117913..1118215 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag C1A40_RS05095 Protein ID WP_102994952.1
Coordinates 1117674..1117916 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1A40_RS05080 1113741..1113989 + 249 WP_158651273.1 hypothetical protein -
C1A40_RS05085 1113993..1114379 + 387 WP_102994950.1 (deoxy)nucleoside triphosphate pyrophosphohydrolase -
C1A40_RS05090 1114376..1117513 + 3138 WP_102994951.1 DEAD/DEAH box helicase -
C1A40_RS05095 1117674..1117916 + 243 WP_102994952.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
C1A40_RS05100 1117913..1118215 + 303 WP_102994953.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C1A40_RS05105 1118391..1119017 + 627 Protein_1008 transposase -
C1A40_RS05110 1119090..1119830 - 741 WP_102994954.1 IS21-like element helper ATPase IstB -
C1A40_RS05115 1119868..1121422 - 1555 Protein_1010 IS21 family transposase -
C1A40_RS05120 1121629..1122894 + 1266 Protein_1011 sialate O-acetylesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-94)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 12285.25 Da        Isoelectric Point: 10.0134

>T92520 WP_102994953.1 NZ_CP025938:1117913-1118215 [Tamlana carrageenivorans]
MSKNKYRISKQAIDDLNDIWVYTFHKWSKEQADRYYDLIIGEIEFIADHYLIGKSAEQTRKNYRVTKIKSHLIFYRKVEH
DIVEIVRILHERMDLKKRLK

Download         Length: 303 bp

>T92520 NZ_CP025938:1117913-1118215 [Tamlana carrageenivorans]
ATGAGTAAAAACAAATATCGAATAAGTAAACAAGCGATTGATGATTTAAATGATATTTGGGTATATACTTTTCACAAATG
GTCTAAAGAACAAGCCGACAGATATTACGACTTGATAATCGGAGAGATTGAATTTATAGCGGACCACTATTTAATTGGAA
AATCGGCTGAACAAACTCGAAAAAACTATCGCGTAACAAAAATCAAATCGCATCTGATTTTTTACAGAAAGGTTGAGCAT
GACATTGTCGAAATCGTTAGAATTTTACATGAAAGAATGGATCTTAAAAAACGACTGAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9270.45 Da        Isoelectric Point: 6.7294

>AT92520 WP_102994952.1 NZ_CP025938:1117674-1117916 [Tamlana carrageenivorans]
MGKNTSISLGNHFEDFIREEVKSGRYGSVSEVIRSALRLLEREEKKERELIKALEVGENSGFIENFDPKQNLTDLHRKHL

Download         Length: 243 bp

>AT92520 NZ_CP025938:1117674-1117916 [Tamlana carrageenivorans]
ATGGGAAAAAACACATCAATTTCACTCGGAAATCATTTTGAGGATTTTATCAGAGAAGAAGTAAAATCAGGCAGATATGG
TTCGGTAAGCGAAGTTATCCGTTCTGCATTACGTTTGCTGGAACGTGAAGAAAAAAAGGAAAGAGAATTAATTAAAGCAC
TCGAAGTAGGTGAAAATAGTGGTTTTATTGAAAATTTTGATCCAAAACAAAACCTGACTGATTTACATCGCAAACACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References