Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2225709..2225943 | Replicon | chromosome |
| Accession | NZ_CP025903 | ||
| Organism | Escherichia coli strain 300709 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2225710..2225813 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2225709..2225943 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CXV43_RS11255 | 2222907..2223716 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| CXV43_RS11260 | 2223773..2223967 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| CXV43_RS11265 | 2223960..2224148 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2223966..2224144 | - | 179 | NuclAT_0 | - | - |
| - | 2223966..2224144 | - | 179 | NuclAT_0 | - | - |
| - | 2223966..2224144 | - | 179 | NuclAT_0 | - | - |
| - | 2223966..2224144 | - | 179 | NuclAT_0 | - | - |
| CXV43_RS11270 | 2224255..2224536 | + | 282 | WP_001311878.1 | excisionase | - |
| CXV43_RS11275 | 2224502..2225578 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2225709..2225943 | + | 235 | - | - | Antitoxin |
| - | 2225710..2225813 | - | 104 | - | - | Toxin |
| CXV43_RS11280 | 2225971..2226312 | - | 342 | WP_000976476.1 | YebY family protein | - |
| CXV43_RS11285 | 2226325..2227197 | - | 873 | WP_000879289.1 | copper homeostasis membrane protein CopD | - |
| CXV43_RS11290 | 2227201..2227575 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| CXV43_RS11295 | 2227714..2227944 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CXV43_RS11300 | 2228046..2228702 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| CXV43_RS11305 | 2228726..2229388 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2185564..2247962 | 62398 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T92350 NZ_CP025903:c2225813-2225710 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT92350 NZ_CP025903:2225709-2225943 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
