Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 128216..128487 Replicon chromosome
Accession NZ_CP025856
Organism Escherichia coli strain 504838

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 128346..128449 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 128216..128487 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXV93_RS00745 124771..125433 - 663 WP_000944256.1 exodeoxyribonuclease X -
CXV93_RS00750 125457..126113 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CXV93_RS00755 126215..126445 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CXV93_RS00760 126584..126958 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CXV93_RS00765 126962..127834 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CXV93_RS00770 127847..128188 + 342 WP_000976492.1 YebY family protein -
- 128216..128487 - 272 - - Antitoxin
- 128346..128449 + 104 - - Toxin
CXV93_RS00775 128584..129240 + 657 WP_000812723.1 protein-serine/threonine phosphatase -
CXV93_RS00780 129241..129432 - 192 WP_001338167.1 YebW family protein -
CXV93_RS00785 129537..129773 - 237 WP_001295499.1 DUF1480 family protein -
CXV93_RS00790 129891..131330 - 1440 WP_001352399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 56835..144327 87492


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T92140 NZ_CP025856:128346-128449 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT92140 NZ_CP025856:c128487-128216 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References