Detailed information of TA system TA091997

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 2076608..2077644
• Replicon: chromosome
• Accession: NZ_CP025804
• Organism: Sulfitobacter sp. SK012

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: C1J03_RS10050
• Protein ID: WP_114886137.1
• Coordinates: 2077069..2077644 (+)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: C1J03_RS10045
• Protein ID: WP_114886135.1
• Coordinates: 2076608..2077072 (+)
• Length: 155 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1J03_RS10030	2071639..2074575	+	2937	WP_114888948.1	cyclic nucleotide-binding domain-containing protein	-
C1J03_RS10035	2074875..2075192	-	318	WP_114886131.1	hypothetical protein	-
C1J03_RS10040	2075554..2076417	+	864	WP_114886133.1	hypothetical protein	-
C1J03_RS10045	2076608..2077072	+	465	WP_114886135.1	helix-turn-helix domain-containing protein	Antitoxin
C1J03_RS10050	2077069..2077644	+	576	WP_114886137.1	PIN domain-containing protein	Toxin
C1J03_RS10055	2077773..2078369	-	597	WP_114886139.1	hypothetical protein	-
C1J03_RS10060	2078602..2078955	+	354	Protein_1966	type II toxin-antitoxin system HipA family toxin	-
C1J03_RS10065	2078952..2079827	+	876	WP_114886144.1	DUF91 domain-containing protein	-
C1J03_RS25305	2079917..2080078	+	162	WP_162798409.1	hypothetical protein	-
C1J03_RS10070	2080223..2082103	-	1881	WP_114888949.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (11-115)

Antitoxin

• Helix-turn-helix domain, group 17 (85-133)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21088.11 Da
• Isoelectric Point: 4.5318

>T91997 WP_114886137.1 NZ_CP025804:2077069-2077644 [Sulfitobacter sp. SK012]
MSDYADRFTALIDANVLACAMRRNIILSLAEAGFFRPRWSDKIMDETAGAIAKITKGGADTVKQRSAMERAFPESCVDGY
ASLEASLELPDPDDRHVLAAAITTSAQVIVTENLKDFPNDILGPFDIDAISADEFISDAIELDPLAAVAALRKMRARFRN
PEMDAEALLQRIKARKLFQTAETLHQFLELL

Nucleotide

• Length: 576 bp

>T91997 NZ_CP025804:2077069-2077644 [Sulfitobacter sp. SK012]
ATGAGTGACTATGCCGACCGTTTCACGGCATTGATTGACGCAAATGTTCTGGCCTGCGCGATGCGTAGAAACATAATTCT
GTCATTGGCTGAGGCTGGATTTTTCCGGCCTCGGTGGAGCGACAAGATTATGGACGAGACTGCCGGTGCAATCGCCAAAA
TCACGAAAGGTGGGGCTGACACAGTCAAGCAGCGTTCTGCTATGGAGCGCGCATTTCCAGAGTCTTGTGTCGACGGGTAT
GCCTCTCTTGAAGCCAGTTTGGAGCTCCCCGACCCGGATGACCGGCACGTTTTGGCCGCGGCTATAACCACTTCTGCGCA
AGTGATAGTGACAGAAAACCTCAAGGATTTTCCAAACGACATCCTTGGTCCATTTGACATAGATGCCATTTCTGCTGATG
AGTTTATTTCTGATGCAATCGAGCTCGATCCACTCGCTGCGGTAGCCGCACTGCGAAAAATGCGCGCCCGGTTCAGAAAC
CCTGAAATGGATGCAGAAGCATTGCTGCAACGGATCAAAGCTCGAAAACTATTTCAAACTGCTGAAACTCTACATCAATT
TCTAGAGCTGCTTTGA

Antitoxin

Protein

• Length: 155 a.a.
• Molecular weight: 17206.83 Da
• Isoelectric Point: 5.0784

>AT91997 WP_114886135.1 NZ_CP025804:2076608-2077072 [Sulfitobacter sp. SK012]
MMMQAKEAFAERLPDQVEIENADSLRRILASQVNGDEAVELRLALGGKQIEPVTLAPALAASLMELLRLVSSGRGFRMIP
VDAELTTQQAADLLNVSRPHLVKLLEDREIAFFKTGRHRRVKAADLFEYKKKRDTDRSDALSDLAAMDMESDLL

Nucleotide

• Length: 465 bp

>AT91997 NZ_CP025804:2076608-2077072 [Sulfitobacter sp. SK012]
ATGATGATGCAAGCAAAAGAAGCGTTCGCAGAGCGTTTACCCGATCAGGTCGAAATTGAAAATGCTGACAGTCTTCGCCG
AATTCTTGCCTCGCAGGTGAACGGTGATGAGGCAGTGGAGCTGCGTCTGGCTCTTGGCGGAAAGCAGATCGAACCAGTGA
CGCTGGCTCCAGCTCTGGCCGCATCCTTGATGGAATTGTTGCGGCTGGTTTCAAGCGGTAGAGGGTTCCGGATGATCCCT
GTTGATGCGGAGCTGACGACCCAGCAAGCAGCTGACTTGTTGAATGTTTCGCGTCCGCATCTCGTGAAACTTCTGGAAGA
CAGGGAAATTGCATTCTTCAAGACCGGAAGGCACCGCCGTGTGAAAGCTGCTGATCTTTTTGAATACAAAAAGAAACGCG
ACACAGACCGCTCTGATGCGCTGTCTGACCTAGCGGCGATGGACATGGAGAGCGATCTTTTATGA