Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2076608..2077644 Replicon chromosome
Accession NZ_CP025804
Organism Sulfitobacter sp. SK012

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag C1J03_RS10050 Protein ID WP_114886137.1
Coordinates 2077069..2077644 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag C1J03_RS10045 Protein ID WP_114886135.1
Coordinates 2076608..2077072 (+) Length 155 a.a.

Genomic Context

C1J03_RS10030C1J03_RS10040C1J03_RS10045C1J03_RS10050C1J03_RS10060C1J03_RS10065C1J03_RS25305C1J03_RS10035C1J03_RS10055C1J03_RS10070
Location: 2071639..2074575 (2937 bp)
Type: Others
Protein ID: WP_114888948.1
Location: 2075554..2076417 (864 bp)
Type: Others
Protein ID: WP_114886133.1
Location: 2076608..2077072 (465 bp)
Type: Antitoxin
Protein ID: WP_114886135.1
Location: 2077069..2077644 (576 bp)
Type: Toxin
Protein ID: WP_114886137.1
Location: 2078602..2078955 (354 bp)
Type: Others
Protein ID: Protein_1966
Location: 2078952..2079827 (876 bp)
Type: Others
Protein ID: WP_114886144.1
Location: 2079917..2080078 (162 bp)
Type: Others
Protein ID: WP_162798409.1
Location: 2074875..2075192 (318 bp)
Type: Others
Protein ID: WP_114886131.1
Location: 2077773..2078369 (597 bp)
Type: Others
Protein ID: WP_114886139.1
Location: 2080223..2082103 (1881 bp)
Type: Others
Protein ID: WP_114888949.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C1J03_RS100302071639..2074575+2937WP_114888948.1cyclic nucleotide-binding domain-containing protein-
C1J03_RS100352074875..2075192-318WP_114886131.1hypothetical protein-
C1J03_RS100402075554..2076417+864WP_114886133.1hypothetical protein-
C1J03_RS100452076608..2077072+465WP_114886135.1helix-turn-helix domain-containing proteinAntitoxin
C1J03_RS100502077069..2077644+576WP_114886137.1PIN domain-containing proteinToxin
C1J03_RS100552077773..2078369-597WP_114886139.1hypothetical protein-
C1J03_RS100602078602..2078955+354Protein_1966type II toxin-antitoxin system HipA family toxin-
C1J03_RS100652078952..2079827+876WP_114886144.1DUF91 domain-containing protein-
C1J03_RS253052079917..2080078+162WP_162798409.1hypothetical protein-
C1J03_RS100702080223..2082103-1881WP_114888949.1AAA family ATPase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(11-115)

Antitoxin

Helix-turn-helix domain, group 17

(85-133)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21088.11 Da        Isoelectric Point: 4.5318

>T91997 WP_114886137.1 NZ_CP025804:2077069-2077644 [Sulfitobacter sp. SK012]
MSDYADRFTALIDANVLACAMRRNIILSLAEAGFFRPRWSDKIMDETAGAIAKITKGGADTVKQRSAMERAFPESCVDGY
ASLEASLELPDPDDRHVLAAAITTSAQVIVTENLKDFPNDILGPFDIDAISADEFISDAIELDPLAAVAALRKMRARFRN
PEMDAEALLQRIKARKLFQTAETLHQFLELL

Download         Length: 576 bp

>T91997 NZ_CP025804:2077069-2077644 [Sulfitobacter sp. SK012]
ATGAGTGACTATGCCGACCGTTTCACGGCATTGATTGACGCAAATGTTCTGGCCTGCGCGATGCGTAGAAACATAATTCT
GTCATTGGCTGAGGCTGGATTTTTCCGGCCTCGGTGGAGCGACAAGATTATGGACGAGACTGCCGGTGCAATCGCCAAAA
TCACGAAAGGTGGGGCTGACACAGTCAAGCAGCGTTCTGCTATGGAGCGCGCATTTCCAGAGTCTTGTGTCGACGGGTAT
GCCTCTCTTGAAGCCAGTTTGGAGCTCCCCGACCCGGATGACCGGCACGTTTTGGCCGCGGCTATAACCACTTCTGCGCA
AGTGATAGTGACAGAAAACCTCAAGGATTTTCCAAACGACATCCTTGGTCCATTTGACATAGATGCCATTTCTGCTGATG
AGTTTATTTCTGATGCAATCGAGCTCGATCCACTCGCTGCGGTAGCCGCACTGCGAAAAATGCGCGCCCGGTTCAGAAAC
CCTGAAATGGATGCAGAAGCATTGCTGCAACGGATCAAAGCTCGAAAACTATTTCAAACTGCTGAAACTCTACATCAATT
TCTAGAGCTGCTTTGA

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17206.83 Da        Isoelectric Point: 5.0784

>AT91997 WP_114886135.1 NZ_CP025804:2076608-2077072 [Sulfitobacter sp. SK012]
MMMQAKEAFAERLPDQVEIENADSLRRILASQVNGDEAVELRLALGGKQIEPVTLAPALAASLMELLRLVSSGRGFRMIP
VDAELTTQQAADLLNVSRPHLVKLLEDREIAFFKTGRHRRVKAADLFEYKKKRDTDRSDALSDLAAMDMESDLL

Download         Length: 465 bp

>AT91997 NZ_CP025804:2076608-2077072 [Sulfitobacter sp. SK012]
ATGATGATGCAAGCAAAAGAAGCGTTCGCAGAGCGTTTACCCGATCAGGTCGAAATTGAAAATGCTGACAGTCTTCGCCG
AATTCTTGCCTCGCAGGTGAACGGTGATGAGGCAGTGGAGCTGCGTCTGGCTCTTGGCGGAAAGCAGATCGAACCAGTGA
CGCTGGCTCCAGCTCTGGCCGCATCCTTGATGGAATTGTTGCGGCTGGTTTCAAGCGGTAGAGGGTTCCGGATGATCCCT
GTTGATGCGGAGCTGACGACCCAGCAAGCAGCTGACTTGTTGAATGTTTCGCGTCCGCATCTCGTGAAACTTCTGGAAGA
CAGGGAAATTGCATTCTTCAAGACCGGAAGGCACCGCCGTGTGAAAGCTGCTGATCTTTTTGAATACAAAAAGAAACGCG
ACACAGACCGCTCTGATGCGCTGTCTGACCTAGCGGCGATGGACATGGAGAGCGATCTTTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References