Detailed information of TA system TA091996

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3143321..3144239
• Replicon: chromosome
• Accession: NZ_CP025800
• Organism: Yersinia ruckeri strain SC09

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NJ56_RS14755
• Protein ID: WP_038242633.1
• Coordinates: 3143321..3143779 (-)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A085U7R3
• Locus tag: NJ56_RS14760
• Protein ID: WP_038242631.1
• Coordinates: 3143793..3144239 (-)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NJ56_RS14725	3139243..3139908	+	666	WP_038275968.1	phage shock protein PspA	-
NJ56_RS14730	3139992..3140219	+	228	WP_038242637.1	envelope stress response membrane protein PspB	-
NJ56_RS14735	3140219..3140578	+	360	WP_004717559.1	envelope stress response membrane protein PspC	-
NJ56_RS14740	3140642..3140884	+	243	WP_087931058.1	phage shock protein PspD	-
NJ56_RS14745	3140865..3142262	+	1398	WP_004717556.1	YcjX family protein	-
NJ56_RS14750	3142259..3143317	+	1059	WP_038242635.1	YcjF family protein	-
NJ56_RS14755	3143321..3143779	-	459	WP_038242633.1	RES domain-containing protein	Toxin
NJ56_RS14760	3143793..3144239	-	447	WP_038242631.1	DUF2384 domain-containing protein	Antitoxin
NJ56_RS14765	3144557..3146164	+	1608	WP_038251390.1	transcriptional regulator TyrR	-
NJ56_RS14770	3146199..3146702	-	504	WP_004717547.1	thiol peroxidase	-
NJ56_RS14775	3146852..3147826	+	975	WP_038275966.1	L-Ala-D/L-Glu epimerase	-
NJ56_RS14780	3147837..3148541	-	705	WP_004717543.1	murein tripeptide amidase MpaA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (94-145)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 17072.55 Da
• Isoelectric Point: 6.6384

>T91996 WP_038242633.1 NZ_CP025800:c3143779-3143321 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Nucleotide

• Length: 459 bp

>T91996 NZ_CP025800:c3143779-3143321 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCACCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16406.87 Da
• Isoelectric Point: 8.0956

>AT91996 WP_038242631.1 NZ_CP025800:c3144239-3143793 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Nucleotide

• Length: 447 bp

>AT91996 NZ_CP025800:c3144239-3143793 [Yersinia ruckeri]
ATGAGAACTTATCACCCAAGCCCGATGGCCAAAGTCAGCGCACTATGGCGTGAGATTGGTCTACCCGCCAGTCGTGGCAC
CGCTTTGGTGGACAGCATAAAACTGGGATTTACTGTGGATGTGATCGACACTATACATTTATGGGCTGATATGCCTAAAT
CTGAAATATTACGCGCTACGGGCATTCCGAGCCGCAGTCTGACGCGCCGTCGTACCCATGATGGGCGTTTTACCCCGGAA
GAAAGCGAACGTATTGCACGGTTTGTCCGGGTTATGGATGCGGCGGTAGATTTGTTCGGTGGTGACCGCACCAAAGCAAC
CGCATGGATGTCGATGCCGGTCAAAGGGCTGGGTAATCGAACGCCCGATTCACTGCTGGAAACCGAAACCGGTGCGTTGG
AAATCTGCGACCTGATTGGTCGTCTCGAACATGGGGTCTTTTCGTGA

Structures

Antitoxin

• AlphaFold DB: A0A085U7R3