91986

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 758564..759098 Replicon chromosome
Accession NZ_CP025800
Organism Yersinia ruckeri strain SC09

Toxin (Protein)


Gene name relE Uniprot ID A0A0T9LYG3
Locus tag NJ56_RS03460 Protein ID WP_038275268.1
Coordinates 758564..758854 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A1JJ37
Locus tag NJ56_RS03465 Protein ID WP_005175264.1
Coordinates 758844..759098 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NJ56_RS03410 753813..754043 - 231 WP_073990333.1 DUF4942 domain-containing protein -
NJ56_RS03415 754193..754321 + 129 Protein_650 helix-turn-helix domain-containing protein -
NJ56_RS03420 754357..754455 + 99 Protein_651 transposase -
NJ56_RS03425 754469..754759 - 291 Protein_652 transposase -
NJ56_RS03430 754764..755162 + 399 Protein_653 DDE-type integrase/transposase/recombinase -
NJ56_RS03435 755181..755467 - 287 Protein_654 hypothetical protein -
NJ56_RS03440 755488..756555 - 1068 WP_038275274.1 macro domain-containing protein -
NJ56_RS03445 756552..757208 - 657 WP_038275272.1 DUF4433 domain-containing protein -
NJ56_RS03450 757211..757786 - 576 WP_038275270.1 DUF4433 domain-containing protein -
NJ56_RS03455 757833..758300 - 468 WP_052173072.1 restriction endonuclease subunit S -
NJ56_RS03460 758564..758854 - 291 WP_038275268.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NJ56_RS03465 758844..759098 - 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NJ56_RS03470 759272..760531 - 1260 Protein_661 integrase arm-type DNA-binding domain-containing protein -
NJ56_RS03475 761046..761990 + 945 WP_038275265.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 755488..778533 23045
- flank IS/Tn - - 754469..754717 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11494.42 Da        Isoelectric Point: 9.9816

>T91986 WP_038275268.1 NZ_CP025800:c758854-758564 [Yersinia ruckeri]
MTFNIDFDERALKEWHKLDKTIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRASGFRLIYQVIDEEIVIWIVAVG
KREDEKAYDIAKKRIQ

Download         Length: 291 bp

>T91986 NZ_CP025800:c758854-758564 [Yersinia ruckeri]
ATGACCTTTAATATCGACTTTGACGAACGGGCATTAAAAGAATGGCACAAACTAGATAAAACTATCCGAGAGCAATTTAA
AAAGAAACTAAGAAAATTACAGGAAAATCCCTATATTGAGTCAGCACGTTTGCACGGTGATCTGGCTGGTTGTTTCAAAA
TAAAATTACGCGCATCTGGCTTTCGGTTGATTTACCAAGTTATCGATGAGGAGATTGTGATTTGGATCGTTGCTGTTGGT
AAACGGGAAGATGAAAAAGCTTATGATATTGCCAAGAAGCGAATCCAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9680.07 Da        Isoelectric Point: 4.8283

>AT91986 WP_005175264.1 NZ_CP025800:c759098-758844 [Yersinia ruckeri]
MSTIQIRVDDELKKSAYQAFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSNQDEDADILAVVRERLKNPAKRIRVN
IDDL

Download         Length: 255 bp

>AT91986 NZ_CP025800:c759098-758844 [Yersinia ruckeri]
ATGAGTACTATCCAAATTCGTGTGGATGATGAACTGAAGAAAAGTGCATATCAGGCGTTTGAAAAACTGAATCTTTCGCC
TTCTGATGCACTACGCCTGTTCCTACGTTATGTTGCAGAGAACGAAAAGCTGCCTTTTTCAGAAGTATCCGTCATGGTCA
GTAATCAAGATGAGGATGCTGATATTTTGGCTGTTGTCCGTGAACGTTTGAAAAATCCTGCAAAGCGTATCAGAGTAAAT
ATTGATGACCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0T9LYG3

Antitoxin

Source ID Structure
AlphaFold DB A1JJ37

References