91985

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 755488..757208 Replicon chromosome
Accession NZ_CP025800
Organism Yersinia ruckeri strain SC09

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag NJ56_RS03445 Protein ID WP_038275272.1
Coordinates 756552..757208 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag NJ56_RS03440 Protein ID WP_038275274.1
Coordinates 755488..756555 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NJ56_RS03395 751766..752050 - 285 WP_038245319.1 antirestriction protein -
NJ56_RS03400 752400..753350 - 951 WP_038275283.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
NJ56_RS03405 753343..753738 - 396 WP_038245317.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
NJ56_RS03410 753813..754043 - 231 WP_073990333.1 DUF4942 domain-containing protein -
NJ56_RS03415 754193..754321 + 129 Protein_650 helix-turn-helix domain-containing protein -
NJ56_RS03420 754357..754455 + 99 Protein_651 transposase -
NJ56_RS03425 754469..754759 - 291 Protein_652 transposase -
NJ56_RS03430 754764..755162 + 399 Protein_653 DDE-type integrase/transposase/recombinase -
NJ56_RS03435 755181..755467 - 287 Protein_654 hypothetical protein -
NJ56_RS03440 755488..756555 - 1068 WP_038275274.1 macro domain-containing protein Antitoxin
NJ56_RS03445 756552..757208 - 657 WP_038275272.1 DUF4433 domain-containing protein Toxin
NJ56_RS03450 757211..757786 - 576 WP_038275270.1 DUF4433 domain-containing protein -
NJ56_RS03455 757833..758300 - 468 WP_052173072.1 restriction endonuclease subunit S -
NJ56_RS03460 758564..758854 - 291 WP_038275268.1 type II toxin-antitoxin system RelE/ParE family toxin -
NJ56_RS03465 758844..759098 - 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
NJ56_RS03470 759272..760531 - 1260 Protein_661 integrase arm-type DNA-binding domain-containing protein -
NJ56_RS03475 761046..761990 + 945 WP_038275265.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 755488..778533 23045
- flank IS/Tn - - 754469..754717 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25230.72 Da        Isoelectric Point: 6.6005

>T91985 WP_038275272.1 NZ_CP025800:c757208-756552 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLTNYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLDQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

>T91985 NZ_CP025800:c757208-756552 [Yersinia ruckeri]
GTGGCCTATGACTACAGCACTAGCCTCAACCCGGAAAAAGCCTTGATCTGGCGCATTGTCCATCGGGACAATATTCCGTG
GATACTGGACAACGGTCTGCACTGTGGCAACAGTCCGGTGCAGGCGGAAGACTGGATTAATATCGGTAACCCGGAGCTTA
TCGACAAACGTGCCGGACATCTGGTGCCAACCGGAATGCGGGGGACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCGATGCTGATGAATATCCGCAGCGGACGTGGCGGCATTAAGCAACGCCCCAATGAGGAGATCGTTATTCTGGT
CAGTAGCCTGCGAAACATGGTGGCGCAAAATGTTTCCTTCGTGTTTACCGATAGCCACGCATATTATAACCTGACTAATT
ACTTTACCGAGCTGGACAGTCTGAACCAGATCGATTGGCCCATTCTACAAGCGCGGGATTTCCGTCGCGATCAGGACGAT
TTGGCCAAGTTCGAACGCTATCAGGCAGAGGCGTTAATTTGGAAGCACTGCCCAATAGCGCTGCTTGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGATCAGTGGTTGTCGCAACGCAATCTGTCAATGCCCGTTCACGCGCGGGCTG
GGTGGTACTTCTCATGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40860.29 Da        Isoelectric Point: 6.6976

>AT91985 WP_038275274.1 NZ_CP025800:c756555-755488 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPINMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIKEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp

>AT91985 NZ_CP025800:c756555-755488 [Yersinia ruckeri]
ATGATTACATTTACACAAGGCAATTTACTGGATGCGCCCGTAGAAGCACTAGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTCCCCATCAATATGAAAGCCTATGCTCTCGCCTGCAAACATAAGC
AGGTAATGACAGGTAAAATGTTTATTACCGAAACCGGCGAACTGATGGGGCCTCGCTGGATTGTCAACTTCCCAACTAAA
CAACACTGGCGCGCAGACTCCCGCATGGAGTGGGTTGAAGACGGCTTGCAGGATTTACGCCGCTTTTTGATCAAAGAGAA
AGTGCAATCTATCGCCATTCCCCCACTGGGGGCGGGTAACGGCGGCCTGAATTGGTCGGACGTTCGGATGCGGATTGAAT
CTGCGCTGGGCGACCTTCAGGACACGGAAATTCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGTACC
GGCGTAAAAAAGCTCACTCCCGCCAGAGCGCTGATTGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCCATTGAACAGCATCAGCAGGAAGATGTGCTGAAACTGC
GGTTTGAGGCGCACTATTACGGCCCCTACGCCCCCAACCTTAACCATCTGCTTAACGCGCTAGATGGCACGTATCTGAAA
GCAGAGAAACGCATCCCGGACACCCAGCCGCTGGATGTGATCTGGTTTAATGATCAGGAAAAAGAACACATCAACCTCTG
GCTGAACAACGAGGCCAAAGAGTGGCTACCGGCGCTTGAGCAGGTCAGTCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCAACCGTTGACTGGCTGCTGACCCGAGGAAAATGCCAGCCCACGCTGGATTCCGTGAAAGAGGGG
CTGCACCAGTGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTCTTTGACGACAAGAATCTGCAATTTGCCAT
CAACCGCGTGATGGAGTTCCATTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References