Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yeeU/CbtA-CbeA
Location 3572384..3573131 Replicon chromosome
Accession NZ_CP025799
Organism Dickeya zeae strain MS2

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag C1O30_RS16175 Protein ID WP_102802208.1
Coordinates 3572384..3572704 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag C1O30_RS16180 Protein ID WP_102802209.1
Coordinates 3572730..3573131 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1O30_RS16155 3568224..3569543 + 1320 WP_102802204.1 site-specific integrase -
C1O30_RS16160 3569618..3570667 - 1050 WP_102802205.1 macro domain-containing protein -
C1O30_RS16165 3570681..3571328 - 648 WP_102802206.1 DUF4433 domain-containing protein -
C1O30_RS16170 3571433..3572266 - 834 WP_102802207.1 DUF4942 domain-containing protein -
C1O30_RS16175 3572384..3572704 - 321 WP_102802208.1 TA system toxin CbtA family protein Toxin
C1O30_RS16180 3572730..3573131 - 402 WP_102802209.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
C1O30_RS16185 3573131..3573604 - 474 WP_012768688.1 DNA repair protein RadC -
C1O30_RS16190 3573635..3574456 - 822 WP_102802210.1 DUF945 domain-containing protein -
C1O30_RS16195 3574553..3575419 - 867 WP_102802211.1 GTPase family protein -
C1O30_RS16200 3576156..3576647 + 492 WP_102802739.1 hypothetical protein -
C1O30_RS16205 3576651..3577817 + 1167 WP_102802212.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(6-105)

Antitoxin

Antitoxin CbeA

(22-121)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11955.60 Da        Isoelectric Point: 5.0757

>T91982 WP_102802208.1 NZ_CP025799:c3572704-3572384 [Dickeya zeae]
MQTPSPSPAREASSCLSPVNVWQQLLTYLLDKHYGLTLNDTPFCEEAEIQAHLDAGVSLPDAVNFLVERYELVRIDRSGF
SWQEQKPFLNAVDILRARRATGLLKP

Download         Length: 321 bp

>T91982 NZ_CP025799:c3572704-3572384 [Dickeya zeae]
ATGCAAACACCATCCCCCTCCCCGGCGCGGGAGGCATCGTCATGCCTGTCACCTGTAAATGTCTGGCAACAGTTATTAAC
TTACCTGCTGGACAAGCACTACGGGCTGACGCTCAACGACACGCCGTTTTGTGAAGAAGCTGAGATCCAGGCCCACCTCG
ACGCCGGAGTTTCGCTGCCGGACGCCGTGAACTTTCTGGTGGAGCGCTATGAGCTGGTGCGCATCGACCGCAGCGGTTTT
AGCTGGCAGGAGCAAAAACCGTTTCTGAACGCGGTCGATATTCTCCGCGCCAGACGCGCCACCGGCCTGCTCAAACCATA
A

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14770.91 Da        Isoelectric Point: 6.9476

>AT91982 WP_102802209.1 NZ_CP025799:c3573131-3572730 [Dickeya zeae]
MPFTVIPSTCQEKRTLSLSDAPEWGLEHTLRPRFGARLVQEGCRLHFLADRAGVTGTFSATVACHLEHRFPLLVRQLEQK
LVTGELDPYRQQRVTLHDGVLTCEADTLGSAGYVYITIYPTTAATPTTTFPLP

Download         Length: 402 bp

>AT91982 NZ_CP025799:c3573131-3572730 [Dickeya zeae]
ATGCCTTTTACCGTCATTCCATCAACCTGTCAGGAGAAAAGAACCTTGTCATTATCGGATGCCCCGGAATGGGGACTTGA
ACACACCCTGAGACCGCGCTTTGGAGCCCGGCTGGTACAGGAGGGGTGTCGCCTGCATTTTCTCGCCGACCGTGCCGGTG
TGACCGGCACTTTCAGTGCAACCGTGGCCTGCCATCTGGAACACCGTTTCCCACTGCTGGTGAGACAACTGGAGCAAAAG
CTTGTGACCGGTGAGCTCGATCCCTACCGACAGCAACGCGTCACGCTGCATGACGGCGTACTGACCTGCGAGGCCGATAC
ACTGGGTAGTGCTGGCTACGTCTATATCACGATTTACCCGACCACGGCGGCCACACCGACAACCACATTCCCTTTACCTT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References