Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1714788..1715538 Replicon chromosome
Accession NZ_CP025799
Organism Dickeya zeae strain MS2

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag C1O30_RS07745 Protein ID WP_102801463.1
Coordinates 1714788..1715045 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag C1O30_RS07750 Protein ID WP_102802692.1
Coordinates 1715053..1715538 (+) Length 162 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1O30_RS07725 1709955..1711268 - 1314 WP_102801461.1 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme -
C1O30_RS07730 1711307..1712344 - 1038 WP_102801462.1 phosphotransferase -
C1O30_RS07735 1712337..1713071 - 735 WP_019844837.1 SDR family oxidoreductase -
C1O30_RS07740 1713198..1714226 - 1029 WP_050568680.1 ABC transporter substrate-binding protein -
C1O30_RS07745 1714788..1715045 + 258 WP_102801463.1 DUF4160 domain-containing protein Toxin
C1O30_RS07750 1715053..1715538 + 486 WP_102802692.1 addiction module antitoxin Antitoxin
C1O30_RS07755 1715624..1716118 - 495 WP_102801464.1 hydrogenase maturation peptidase HycI -
C1O30_RS07760 1716111..1716509 - 399 WP_102801465.1 formate hydrogenlyase maturation HycH family protein -
C1O30_RS07765 1716509..1717297 - 789 WP_012885279.1 NADH-quinone oxidoreductase subunit B family protein -
C1O30_RS07770 1717294..1717863 - 570 WP_016943631.1 hydrogenase 4 subunit H -
C1O30_RS07775 1717874..1719601 - 1728 WP_019844844.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Uncharacterized protein HI1420

(80-156)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9867.50 Da        Isoelectric Point: 7.5565

>T91972 WP_102801463.1 NZ_CP025799:1714788-1715045 [Dickeya zeae]
MPEIDRLAGLIFHLYFYDDERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNTKRKLAIAHIMVHREQLLSMWAQAVIGK
NPGKL

Download         Length: 258 bp

>T91972 NZ_CP025799:1714788-1715045 [Dickeya zeae]
ATGCCTGAGATTGACAGACTGGCAGGGTTAATCTTCCATTTGTACTTTTACGATGATGAGCGGCACCACTTGCCGCATGT
GCATGTCTGCTACGGCAATCATGAACTTATCATCAGTATTCGTACCGGAACCGAGATAGAGGGATATCTGCCAAATACCA
AACGTAAGCTGGCGATTGCCCATATCATGGTGCATCGTGAGCAATTGCTGAGTATGTGGGCACAGGCGGTCATCGGGAAG
AATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 162 a.a.        Molecular weight: 17920.34 Da        Isoelectric Point: 6.9893

>AT91972 WP_102802692.1 NZ_CP025799:1715053-1715538 [Dickeya zeae]
MHKIVDVDVVGDFSLRLTYDDGLIYDVNLYRYASYPVFSHASQFIRFGLLPDGSLEWPDITISSSALREKGTYVGHTLAV
RERNFADIISRAFYDAVIENRPEILQAALKIAVDKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLEE
K

Download         Length: 486 bp

>AT91972 NZ_CP025799:1715053-1715538 [Dickeya zeae]
ATGCATAAGATTGTGGATGTTGACGTGGTTGGTGATTTTTCGTTGCGTCTGACCTATGACGACGGCCTGATATACGACGT
TAACCTGTATCGCTATGCCTCATATCCTGTATTTTCACATGCCAGCCAGTTTATCCGATTTGGGTTATTACCTGATGGTT
CGCTGGAATGGCCGGATATCACGATCTCTTCGTCCGCATTACGGGAAAAGGGGACGTATGTTGGCCATACGCTGGCGGTG
AGGGAGCGGAATTTTGCCGATATTATCTCCCGAGCCTTCTATGATGCCGTGATTGAGAACCGGCCAGAAATTCTGCAGGC
GGCACTGAAAATCGCAGTAGACAAACATGGTAACAGTACGGTGGCCAAAGAAGCGGGAGCCAAAAGCCGTACCAGCTTGT
ATAAATCGCTGAATAAAAACACCAATGTCAGCCTGGCGACGGTGGTGAGCCTGGCCCACACCGTGTTGCAACTAGAAGAG
AAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References