Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 583841..584367 Replicon chromosome
Accession NZ_CP025799
Organism Dickeya zeae strain MS2

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag C1O30_RS02660 Protein ID WP_102800987.1
Coordinates 583841..584146 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag C1O30_RS02665 Protein ID WP_102800988.1
Coordinates 584149..584367 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1O30_RS02640 579725..580225 + 501 WP_102800984.1 serine acetyltransferase -
C1O30_RS02645 580333..580626 + 294 WP_038903249.1 DUF1778 domain-containing protein -
C1O30_RS02650 580623..581111 + 489 WP_102800985.1 GNAT family N-acetyltransferase -
C1O30_RS02655 581269..583470 + 2202 WP_102800986.1 AAA family ATPase -
C1O30_RS02660 583841..584146 - 306 WP_102800987.1 type II toxin-antitoxin system toxin CcdB Toxin
C1O30_RS02665 584149..584367 - 219 WP_102800988.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
C1O30_RS02675 585042..585617 - 576 WP_102800989.1 transcriptional regulator -
C1O30_RS02680 585710..587458 - 1749 WP_102800990.1 protein-disulfide reductase DsbD -
C1O30_RS02685 587434..587796 - 363 WP_102802664.1 divalent cation tolerance protein CutA -
C1O30_RS02690 587911..589212 - 1302 WP_019843755.1 anaerobic C4-dicarboxylate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11632.45 Da        Isoelectric Point: 4.6389

>T91968 WP_102800987.1 NZ_CP025799:c584146-583841 [Dickeya zeae]
MQFIVYQYKRASHYKMFIDVQSDIVDTPGRRMVIPLIEAHHLSDKVNKTLFPLIRIEGEDYRLMTTELSSVPVEVVGEAL
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

>T91968 NZ_CP025799:c584146-583841 [Dickeya zeae]
ATGCAATTCATTGTTTATCAATACAAACGCGCCAGCCACTACAAAATGTTTATCGATGTACAAAGTGATATTGTCGATAC
GCCAGGGCGACGAATGGTCATTCCGCTTATCGAAGCGCATCACCTGTCTGATAAAGTGAATAAAACATTGTTCCCGCTGA
TCCGCATCGAAGGCGAAGATTATCGACTGATGACCACTGAGCTATCGAGCGTTCCGGTTGAGGTGGTTGGGGAGGCTCTC
GCGGATCTTGGCGACTACGCGGATGAGATTAAGGATGCTATTAATCTTATGTTTTGGGGGATTTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8148.14 Da        Isoelectric Point: 8.6383

>AT91968 WP_102800988.1 NZ_CP025799:c584367-584149 [Dickeya zeae]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDVIGKEARRIKAEAWKKENREGMEEVARFIAQNGSFADENRNW

Download         Length: 219 bp

>AT91968 NZ_CP025799:c584367-584149 [Dickeya zeae]
ATGAAACACCGCGTTAGCGTTACCGTGGACAAAGACAATTATCAGGTTCTGAGTGCTGCCGGAGTCAACATTTCCGGGCT
GGTGAATGATGTCATTGGCAAAGAAGCCCGCCGCATCAAAGCTGAAGCGTGGAAGAAGGAAAACCGCGAAGGGATGGAAG
AAGTCGCCCGATTTATCGCACAGAATGGCTCCTTTGCGGATGAAAACAGGAACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References