Detailed information of TA system TA091964

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /GNAT-DUF1778
• Location: 141857..142623
• Replicon: chromosome
• Accession: NZ_CP025794
• Organism: Vibrio hyugaensis strain 090810a

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: C1S74_RS01325
• Protein ID: WP_045398052.1
• Coordinates: 141857..142354 (-)
• Length: 166 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: C1S74_RS01330
• Protein ID: WP_045398049.1
• Coordinates: 142351..142623 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1S74_RS01250	136996..137106	+	111	WP_103415314.1	DUF3265 domain-containing protein	-
C1S74_RS01255	137139..137681	+	543	WP_045399162.1	GNAT family N-acetyltransferase	-
C1S74_RS01260	137696..137788	+	93	WP_077261317.1	DUF3265 domain-containing protein	-
C1S74_RS01265	137817..138515	+	699	WP_045399160.1	hypothetical protein	-
C1S74_RS01275	138678..139028	+	351	WP_010448889.1	nucleotide pyrophosphohydrolase	-
C1S74_RS01280	139043..139135	+	93	WP_004748931.1	DUF3265 domain-containing protein	-
C1S74_RS01285	139163..139510	+	348	WP_052437299.1	DNA-binding protein	-
C1S74_RS01290	139512..139628	+	117	WP_082039039.1	DUF3265 domain-containing protein	-
C1S74_RS01295	139657..140010	+	354	WP_045399157.1	glyoxalase/bleomycin resistance/dioxygenase family protein	-
C1S74_RS26615	140028..140117	+	90	WP_072875472.1	DUF3265 domain-containing protein	-
C1S74_RS01305	140572..140664	+	93	WP_017821981.1	DUF3265 domain-containing protein	-
C1S74_RS01310	141120..141212	+	93	WP_080936824.1	DUF3265 domain-containing protein	-
C1S74_RS01320	141671..141823	+	153	WP_103415317.1	DUF3265 domain-containing protein	-
C1S74_RS01325	141857..142354	-	498	WP_045398052.1	GNAT family N-acetyltransferase	Toxin
C1S74_RS01330	142351..142623	-	273	WP_045398049.1	DUF1778 domain-containing protein	Antitoxin
C1S74_RS01340	143346..143435	+	90	WP_072612530.1	DUF3265 domain-containing protein	-
C1S74_RS01350	143923..144054	+	132	WP_017420680.1	DUF3265 domain-containing protein	-
C1S74_RS01355	144081..144467	+	387	WP_045398047.1	hypothetical protein	-
C1S74_RS01360	144464..144574	+	111	WP_082039007.1	DUF3265 domain-containing protein	-
C1S74_RS01365	145029..145121	+	93	WP_197064541.1	DUF3265 domain-containing protein	-
C1S74_RS26495	145278..145529	+	252	WP_082039006.1	hypothetical protein	-
C1S74_RS01375	145651..145740	+	90	WP_082039005.1	DUF3265 domain-containing protein	-
C1S74_RS01380	145780..146181	+	402	WP_031856960.1	hypothetical protein	-
C1S74_RS01385	146191..146373	+	183	WP_045398041.1	hypothetical protein	-
C1S74_RS01390	146506..147063	+	558	WP_045398039.1	nucleotidyltransferase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	44410..164172	119762

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (86-152)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-89)

Sequences

Toxin

Protein

• Length: 166 a.a.
• Molecular weight: 18512.16 Da
• Isoelectric Point: 8.0187

>T91964 WP_045398052.1 NZ_CP025794:c142354-141857 [Vibrio hyugaensis]
MMNTVLLDKAKHDRNRFNCGIEALNNYLKVMASQQAKKDNTRTFVLEDDNDNSYVIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKHFYERYGFQAFEDAENKLFITIADV
RASLG

Nucleotide

• Length: 498 bp

>T91964 NZ_CP025794:c142354-141857 [Vibrio hyugaensis]
ATGATGAATACGGTACTTCTAGATAAAGCTAAACACGATAGAAACCGATTCAACTGTGGTATCGAAGCTCTCAATAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCAAAAAAAGACAACACCAGAACGTTTGTTTTGGAAGATGATAACGACAACTCAT
ATGTCATCGGCTTTTACACGCTAACAATGACACCAATTGACTTAAAGGCATTACCCGATAAGTTACAAAAAAAACACCAA
TCATCCACCTCTGGTGGTCTGATTGCCCGCCTTGCTGTCGATGACCGATACAAAGGGAAAGGCTTTGGTGAGTGGCTGCT
TATTGACGCACTCAGAAAGCTATTAGCTGCAAGTGATAGCGTTGCATTTCCAGTTGTTATCGTTGATGCCAAAGACGGTG
CGAAACACTTCTATGAACGCTATGGTTTTCAAGCATTTGAAGACGCTGAAAATAAACTCTTCATCACCATTGCTGATGTG
AGAGCAAGCTTAGGCTAG

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9749.25 Da
• Isoelectric Point: 8.5960

>AT91964 WP_045398049.1 NZ_CP025794:c142623-142351 [Vibrio hyugaensis]
MATTLPRITARVDIDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQADAMLLMEALDRPATQNSKLKA
AADRYESKTQ

Nucleotide

• Length: 273 bp

>AT91964 NZ_CP025794:c142623-142351 [Vibrio hyugaensis]
ATGGCTACTACTTTGCCTCGCATCACCGCTAGAGTTGATATCGATACACAAGACTTACTTACTAAGGCTGCCGCGATCGC
CGGCATGTCTAGCATTAACTCGTTTGTTCTAAGCGCTGCAATCGAAAAAGCCAAACAAGTTATCGAACGTGAACAGGCTT
TAAAACTGAGCCAAGCTGATGCTATGTTGCTGATGGAAGCTTTAGACCGCCCTGCTACACAGAACTCAAAACTAAAAGCT
GCTGCTGATCGATACGAGAGCAAAACTCAATGA