Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 82152..82680 Replicon chromosome
Accession NZ_CP025794
Organism Vibrio hyugaensis strain 090810a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C1S74_RS00640 Protein ID WP_045401004.1
Coordinates 82152..82442 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C1S74_RS00645 Protein ID WP_045401001.1
Coordinates 82432..82680 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1S74_RS00575 77503..77973 + 471 WP_045402130.1 GNAT family N-acetyltransferase -
C1S74_RS00585 78536..78628 + 93 WP_167391138.1 DUF3265 domain-containing protein -
C1S74_RS00590 78659..79180 + 522 WP_045402127.1 GNAT family N-acetyltransferase -
C1S74_RS00595 79211..79303 + 93 WP_078231741.1 DUF3265 domain-containing protein -
C1S74_RS00600 79390..79827 - 438 WP_167391134.1 hypothetical protein -
C1S74_RS00605 79791..79922 + 132 WP_082039089.1 DUF3265 domain-containing protein -
C1S74_RS00615 80444..80533 + 90 WP_075984317.1 DUF3265 domain-containing protein -
C1S74_RS00620 80584..80913 + 330 WP_045402124.1 hypothetical protein -
C1S74_RS00625 80938..81030 + 93 WP_197064556.1 DUF3265 domain-containing protein -
C1S74_RS00630 81058..81507 + 450 WP_052437317.1 hypothetical protein -
C1S74_RS00635 82041..82133 + 93 WP_082039066.1 DUF3265 domain-containing protein -
C1S74_RS00640 82152..82442 - 291 WP_045401004.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C1S74_RS00645 82432..82680 - 249 WP_045401001.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C1S74_RS00650 82755..82823 + 69 WP_077672877.1 DUF3265 domain-containing protein -
C1S74_RS00660 82876..84273 + 1398 WP_045400999.1 hypothetical protein -
C1S74_RS00670 84528..84827 + 300 WP_082039064.1 hypothetical protein -
C1S74_RS00675 84838..85218 + 381 WP_045400997.1 hypothetical protein -
C1S74_RS00680 85388..85789 + 402 WP_045400994.1 HIT family protein -
C1S74_RS00690 86444..86536 + 93 WP_005377014.1 DUF3265 domain-containing protein -
C1S74_RS00695 86660..87217 + 558 WP_049877468.1 hypothetical protein -
C1S74_RS00700 87224..87334 + 111 WP_103415314.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 44410..164172 119762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11308.26 Da        Isoelectric Point: 10.5932

>T91962 WP_045401004.1 NZ_CP025794:c82442-82152 [Vibrio hyugaensis]
MTYKLDFKKSALKEWKKLGSTIQQQFKKKLIERLDNPHVQASKLSGSDNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYRKAMKRLDD

Download         Length: 291 bp

>T91962 NZ_CP025794:c82442-82152 [Vibrio hyugaensis]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCAACGATTCAACAACAATTTAA
GAAAAAGCTAATCGAGCGTTTAGATAACCCGCATGTTCAGGCTTCAAAACTCTCTGGATCTGACAACATGTATAAGATTA
AGCTGCGCCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGCGAACGTAGCGATGTTTACCGTAAAGCTATGAAAAGGTTAGATGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9108.41 Da        Isoelectric Point: 4.0078

>AT91962 WP_045401001.1 NZ_CP025794:c82680-82432 [Vibrio hyugaensis]
MTTRILADVAASITELKANPMKVATSAYGQPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLTIAKERESEESISVNID
DL

Download         Length: 249 bp

>AT91962 NZ_CP025794:c82680-82432 [Vibrio hyugaensis]
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGCGC
TTACGGTCAACCTGTCGCTGTACTGAACCGAAATGAGCCAGCATTTTATTGCGTACCAGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTTACTATTGCGAAGGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References